Performance of a rapid molecular test to detect Chlamydia trachomatis and Neisseria gonorrhoeae in women with pelvic inflammatory disease.

Enferm Infecc Microbiol Clin (Engl Ed)

Institut de Salut Global Barcelona - ISGlobal, Barcelona, Spain; Department of Microbiology, Biomedical Diagnostic Center (CDB), Hospital Clínic of Barcelona, University of Barcelona, Barcelona, Spain.

Published: May 2021

AI Article Synopsis

  • The study aimed to explore how common Chlamydia trachomatis and Neisseria gonorrhoeae infections are in women with pelvic inflammatory disease, as well as the effectiveness and cost-efficiency of a rapid testing method.
  • A total of 75 patients were examined, with 19 of them (25.3%) testing positive for the infections, and both rapid and standard tests showed 100% agreement.
  • The findings suggest that rapid molecular tests could be beneficial for diagnosing pelvic inflammatory disease, especially in situations where standard testing isn't accessible.

Article Abstract

Objective: The aim of this study was to investigate the prevalence of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) in women with pelvic inflammatory disease (PID) and the usefulness and cost-effectiveness of a rapid molecular test for the diagnosis and clinical management of PID.

Methods: This observational study included 75 patients with mild-to-moderate PID (n=33), severe PID (n=29) and non-specific lower abdominal pain (NSAP) (n=13). CT/NG infections were analyzed using a standard and a rapid test. A cost analysis was carried out.

Results: Samples of 19 patients (25.3%) were CT/NG positive. Concordance between rapid and standard tests was 100%. No significant differences were observed in the incidence of CT/NG in mild-to-moderate compared to severe PID. Costs differed according only to disease severity.

Conclusions: Rapid molecular tests could help with the diagnosis of PID in sexually active women in clinical settings in which a standard technique is not available.

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Source
http://dx.doi.org/10.1016/j.eimc.2021.03.016DOI Listing

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