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Practical concepts and strategies for early diagnosis and management of eosinophilic gastrointestinal disorders in East-Asian children.
Clin Exp Pediatr
November 2024
Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, Korea.
Eosinophilic gastrointestinal disorders (EGIDs) are emerging as significant concerns in the Korean pediatric population and transitioning from rare to more commonly diagnosed conditions. This review discusses the increasing prevalence of EGID among children and adolescents and highlights the complexities involved in its diagnosis and management. This review begins with a thorough examination of the diverse clinical presentations of EGIDs in Korean children, with a special focus on common gastrointestinal symptoms such as abdominal pain, diarrhea, and bloody stool.
View Article and Find Full Text PDFFood-Protein-Induced Proctocolitis in Pre-Term Newborns with Bloody Stools in a Neonatal Intensive Care Unit.
Nutrients
September 2024
Division of Neonatology and Neonatal Intensive Care Unit, Buzzi Children's Hospital, 20154 Milan, Italy.
Article Synopsis
- Bloody stools in newborns can indicate various conditions, including idiopathic neonatal transient colitis, food-protein-induced allergic proctocolitis (FPIAP), and necrotizing enterocolitis (NEC), with distinct treatments and prognoses for each.
- A study of pre-term infants in the NICU revealed that NEC patients had lower eosinophil counts and higher procalcitonin levels, as well as more severe abdominal ultrasound and X-ray findings compared to those with FPIAP or transient colitis.
- Differentiating between idiopathic neonatal transient colitis and FPIAP is difficult without lab markers or imaging, so confirmation of FPIAP requires an oral food challenge
Schistosomal colitis mimicking inflammatory bowel disease: a case report from Sudan.
Ann Med Surg (Lond)
August 2024
Consultant Physician and Gastroenterologist, Director of The National Center for Gastrointestinal and Liver Diseases, Khartoum, Sudan.
Introduction: Schistosomiasis, caused by parasitic Schistosoma species, is a common neglected tropical disease prevalent in sub-Saharan Africa, including Sudan. While urinary tract infections are more frequent, intestinal schistosomiasis is rare. The disease presents with nonspecific symptoms, often leading to misdiagnosis as inflammatory bowel disease (IBD).
View Article and Find Full Text PDFA case of eosinophilic granulomatosis with polyangiitis associated with diffuse alveolar haemorrhage: A case report and case-based review.
Mod Rheumatol Case Rep
July 2024
Department of Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
A 76-year-old man with bronchial asthma was admitted for respiratory failure and bloody sputum. A significant drop in haemoglobin and multiple consolidations supported clinical diagnosis of diffuse alveolar haemorrhage (AH). Myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) was positive and urinalysis suggested glomerulonephritis.
View Article and Find Full Text PDF[Clinical characteristics of 267 children with eosinophilic gastrointestinal disease: a multicenter study].
Zhongguo Dang Dai Er Ke Za Zhi
February 2024
Department of Gastroenterology, Jiangxi Children's Hospital, Nanchang 330000, China (Wan S-H, Email: jeft1210@ 126. com).
Objectives: To explore the clinical manifestations, endoscopic findings, histopathological changes, treatment, and prognosis of eosinophilic gastrointestinal disease (EGID) in children, with the aim of enhancing awareness among pediatricians about this condition.
Methods: Data of 267 children with EGID were prospectively collected from January 2019 to July 2022 at Jiangxi Children's Hospital, Hunan Children's Hospital, and Henan Children's Hospital. The age of onset, symptoms, physical signs, laboratory examination results, endoscopic findings, histopathological changes, and treatment outcomes were observed.
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