An epidemiological investigation on the incidence of HSV2 infection in 1216 women with acute or recurrent vulvovaginitis was performed. HSV2 research was carried out by means of clinical, cytological, colposcopic, histologic examinations and vaginal pad cultures and antibody titration. Of the patients examined, 12.6% presented signs of genital herpes; among the diagnostic techniques used, the most reliable proved to be the serological method. Incidence of HSV2 was higher among women in the under privileged social classes, those who had sexual relations with different partners and those who were multiparous. A higher percentage of dysplastic and/or neoplastic lesions of the uterine cervix among HSV2 positive (P less than 0.025) with respect to controls was also found. A higher incidence of neoplastic pathologies among women who are positive for HSV2 was therefore confirmed.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Navigating herpes simplex encephalitis: Family medicine perspectives from Jharkhand, India.
J Family Med Prim Care
December 2024
Department of Microbiology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Background: Herpes simplex encephalitis (HSE), caused by herpes simplex virus (HSV) is the most common cause of sporadic encephalitis that often presents as an emergency case of acute or sub-acute nature associated with poor prognosis. Early suspicion and prompt diagnostic testing with adequate antiviral therapy can only reduce morbidity and mortality associated with the disease. This study aims to evaluate the role of serological and molecular diagnosis of encephalitis caused by HSV 1 and 2 for timely detection of the disease.
View Article and Find Full Text PDFSeroprevalence of HSV-2 in multiple subgroups of infertile men with abnormal sperm parameters and those seeking sex selection: a case-control study.
BMC Infect Dis
January 2025
Reproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Background: Herpes simplex virus type 2 (HSV-2) is a common sexually transmitted infection (STI) primarily acquired through sexual contact. In 2000, the World Health Organization (WHO) for the first time reported the association of STIs with male infertility. Infertility is described as the inability to achieve a clinical pregnancy after engaging in regular, unprotected sexual intercourse for a year or more.
View Article and Find Full Text PDFHerpes simplex virus type 2 in sub-Saharan Africa and the potential impact of helminth immune modulation.
Front Cell Infect Microbiol
December 2024
Department of Medical Microbiology, College of Health Sciences, School of Laboratory Medicine & Medical Sciences, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
Herpes simplex virus type 2 (HSV-2) and helminth infections are among the most widespread infectious diseases in sub-Saharan Africa (SSA). Helminths are known to modulate host immune responses and consequently impact the severity and outcomes of unrelated diseases, including allergies, autoimmune conditions, and infectious diseases. In this way, helminths may modulate essential immune responses against HSV-2 during co-infection and may alter susceptibility to and pathology of HSV-2.
View Article and Find Full Text PDFEstimated global and regional incidence and prevalence of herpes simplex virus infections and genital ulcer disease in 2020: mathematical modelling analyses.
Sex Transm Infect
December 2024
Population Health Sciences, University of Bristol, Bristol, UK.
Objectives: Genital herpes simplex virus (HSV) type 1 and 2 infections are lifelong and can cause symptomatic genital ulcer disease (GUD). HSV-2 almost always causes sexually transmitted genital infection, while HSV-1 mainly causes oral infection but can be sexually transmitted to cause genital infection. This study estimated genital infection with both HSV types and associated GUD globally in 2020, breaking down the data by WHO region and sex for females and males.
View Article and Find Full Text PDFMortality and prognosis in herpes simplex Virus-1 encephalitis long-term follow up study.
J Neurol Sci
November 2024
Department of Neurology, Rambam Medical Center, Haifa, Israel; AI in Neurology Laboratory, Ruth and Bruce Rapaport Faculty of Medicine, Technion Institute of Technology, Haifa 3525408, Israel; Department of Neurology, Mayo Clinic, Rochester, MN, United States of America. Electronic address:
Article Synopsis
- Herpes simplex virus-1 (HSV-1) encephalitis is the most common type of viral encephalitis globally, but there is limited understanding of long-term mortality rates and influencing factors.
- A retrospective study analyzed data from HSV-positive encephalitis patients over 23 years, finding that 55.31% of HSV-1 patients died during follow-up, with older age and cancer comorbidities significantly increasing mortality risk.
- Key findings highlighted that older patients had a higher risk of death, and having cancer dramatically impacted mortality, with an optimal age cut-off of 63.29 years identified for predicting outcomes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!