AI Article Synopsis
- Hidradenitis suppurativa, also known as Acne inversa, is a chronic skin condition that causes painful nodules, abscesses, and scarring, primarily in areas where skin rubs together.
- The condition affects 0.05 to 4.1% of the population, with a higher prevalence in women, and may be linked to factors like smoking, obesity, and genetic mutations.
- Treatment varies by severity, with mild cases often managed using topical clindamycin, while more severe cases may need systemic anti-inflammatory medications, and only surgery offers a definitive solution.
Article Abstract
CME Dermatology 23: Hidradenitis suppurativa Hidradenitis suppurativa (Acne inversa) is a chronic skin disease characterized by recurrent inflammatory nodules, abscesses, and scarring mainly in the intertriginous areas. The prevalence is estimated to be 0.05 to 4.1 % worldwide, with women being more commonly affected. The exact pathogenesis remains unknown, but hair follicle occlusion and inflammation seem to be the initiating events. Several epidemiological correlations with smoking and obesity as well as mutations in gamma secretase genes were described. The therapy depends on the extension of the disorder and should respect the current guidelines. Topical clindamycin is suitable for mild forms of the disease whereas moderate to severe disease requires systemic anti-inflammatory treatment. Surgical intervention is currently the only definitive treatment for hidradenitis suppurativa.
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| http://dx.doi.org/10.1024/1661-8157/a003693 | DOI Listing |
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