Spillover of zoonotic pathogens: A review of reviews.

Zoonoses Public Health

Odum School of Ecology, University of Georgia, Athens, GA, USA.

Published: September 2021

Zoonotic spillover and subsequent disease emergence cause significant, long-lasting impacts on our social, economic, environmental and political systems. Identifying and averting spillover transmission is crucial for preventing outbreaks and mitigating infectious disease burdens. Investigating the processes that lead to spillover fundamentally involves interactions between animals, humans, pathogens and the environments they inhabit. Accordingly, it is recognized that transdisciplinary approaches provide a more holistic understanding of spillover phenomena. To characterize the discourse about spillover within and between disciplines, we conducted a review of review papers about spillover from multiple disciplines. We systematically searched and screened literature from several databases to identify a corpus of review papers from ten academic disciplines. We performed qualitative content analysis on text where authors described either a spillover pathway, or a conceptual gap in spillover theory. Cluster analysis of pathway data identified nine major spillover processes discussed in the review literature. We summarized the main features of each process, how different disciplines contributed to them, and identified specialist and generalist disciplines based on the breadth of processes they studied. Network analyses showed strong similarities between concepts reviewed by 'One Health' disciplines (e.g. Veterinary Science & Animal Health, Public Health & Medicine, Ecology & Evolution, Environmental Science), which had broad conceptual scope and were well-connected to other disciplines. By contrast, awas focused on processes that are relatively overlooked by other disciplines, especially those involving food behaviour and livestock husbandry practices. Virology and Cellular & Molecular Biology were narrower in scope, primarily focusing on concepts related to adaption and evolution of zoonotic viruses. Finally, we identified priority areas for future research into zoonotic spillover by studying the gap data.

Download full-text PDF

Source
http://dx.doi.org/10.1111/zph.12846DOI Listing

Publication Analysis

Top Keywords

spillover
11
zoonotic spillover
8
disciplines
8
review papers
8
review
5
spillover zoonotic
4
zoonotic pathogens
4
pathogens review
4
review reviews
4
reviews zoonotic
4

Similar Publications

Workplace Violence Is Home Now for Healthcare Workers: Spillover Theory Perspective.

Stress Health

February 2025

Marketing, International Business and Tourism Department, Manchester Metropolitan University, Manchester, UK.

In recent years, workplace violence has become an escalating concern, particularly within the healthcare sector. Healthcare workers, who dedicate their lives to caring for others, are increasingly facing violence within their workplaces as evidenced by existing studies. However, literature overlooks complex associations between workplace violence, workplace stress, and domestic violence and stress.

View Article and Find Full Text PDF

ConspectusThe discovery of reversible hydrogenation using metal-free phosphoborate species in 2006 marked the official advent of frustrated Lewis pair (FLP) chemistry. This breakthrough revolutionized homogeneous catalysis approaches and paved the way for innovative catalytic strategies. The unique reactivity of FLPs is attributed to the Lewis base (LB) and Lewis acid (LA) sites either in spatial separation or in equilibrium, which actively react with molecules.

View Article and Find Full Text PDF

The development and implementation of county carbon control action plans in the Yellow River Basin (YRB) are crucial for realizing the "dual carbon" goals and modernizing national governance. Utilizing remote sensing data from 2001 to 2020, this study constructs a light-carbon conversion model and a carbon footprint model to simulate the carbon footprint of county energy consumption in the YRB. Employing spatial autocorrelation and spatial Durbin models, the study examines the temporal-spatial evolution characteristics and spatial effect mechanism.

View Article and Find Full Text PDF

The reform of rural collective property rights system is of great significance for protecting the collective asset rights and interests of villagers, activating rural resource elements, and achieving rural revitalization. This study is based on 284 village committee questionnaires and 7451 villager questionnaires from 10 provinces in China, and uses multi-layer linear regression models to explore the impact of the reform of rural collective property rights system on villagers' public participation. Research has found that:(1) the reform of rural collective property rights system that has been completed at the rural level can significantly enhance the public participation of villagers, including total participation (β = 0.

View Article and Find Full Text PDF

SARS-CoV-2 nonstructural protein 1 (nsp1) promotes innate immune evasion by inhibiting host translation in human cells. However, the role of nsp1 in other host species remains elusive, especially in bats which are natural reservoirs of sarbecoviruses and possess a markedly different innate immune system than humans. Here, we reveal that SARS-CoV-2 nsp1 potently inhibits translation in bat cells from Rhinolophus lepidus, belonging to the same genus as known sarbecovirus reservoirs hosts.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!