Four undescribed sulfoxide-containing derivatives, sinkiangenoxides A and B, (2, 4)-sinkiangenoxide C, and (2, 4)-sinkiangenoxide C (1: - 4: ), and one known compound, 1-(methylthio)propyl ()-1-propenyl disulfide (5: ), were isolated from the resin of . Their structures were determined based on spectroscopic methods, including IR, UV, HRESIMS, NMR, and CD analysis. Compounds 2: - 4: showed moderate cytotoxic activities against four human cancer cell lines with IC values ranging from 15.0 to 40.3 µM. Sinkiangenoxide B (2: ) was shown to induce apoptosis in HepG2 cells. In addition, compound 5: effectively attenuated lipopolysaccharide-induced nitric oxide release and TNF-, IL-1, IL-6, and IL-10 expression.
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