Background: Invasive fusariosis is a serious infection affecting mostly patients with haematologic malignancies and hematopoietic cell transplant recipients.
Objectives: To develop a scoring tool that evaluates guideline adherence in the management of invasive fusariosis.
Methods: We reviewed two guidelines, provided by the European Society for Clinical Microbiology and Infectious Diseases (ESCMID) and the European Confederation of Medical Mycology (ECMM), and selected the strongest recommendations for management quality as the bases for the scoring tool.
Results: We reviewed the recommendations regarding primary and secondary prophylaxis, diagnostics procedures (images, blood cultures, biopsy of skin lesions with direct examination, culture and histopathology, species identification, antifungal susceptibility tests and antigen detection), treatment choices and follow-up procedures. The tool comprises 18 items, with a maximum of 24 points.
Conclusions: The EQUAL score Fusariosis is a tool that may help clinicians to measure guidelines adherence.
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http://dx.doi.org/10.1111/myc.13321 | DOI Listing |
Environ Epidemiol
February 2025
Saarland University, Institute of Sports and Preventive Medicine, Campus Geb B8 2, Saarbrücken, Germany.
A cross-sectional analysis was performed to investigate associations between environmental temperatures and injury occurrence in two professional male football (soccer) leagues. Data from seven seasons of the German Bundesliga (2142 matches) and four seasons of the Australian A-League (470 matches) were included. Injuries were collated via media reports for the Bundesliga and via team staff reports in the A-League and comprised injury incidence, mechanisms (contact, noncontact), locations (e.
View Article and Find Full Text PDFSports (Basel)
November 2024
Confédération Européenne de Volleyball, Grand Duchy of Luxembourg, 1940 Luxembourg, Luxembourg.
Volleyball referees, as athletes and staff members, are exposed to different stress levels which can be determined by measuring pre- and post-match levels of salivary cortisol (C) and alpha-amylase (AA). This study aimed to determine the dynamics of stress biomarkers in referees during official volleyball matches and the connection to the roles or level of competition. The participants in this study were nine international volleyball referees (three females and six males) with a mean chronological age of 48.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
December 2024
Research Committee of Young-Otolaryngologists of the International Federations of Oto-rhino- laryngological Societies (YO-IFOS), Paris, France.
Objective: To propose a European consensus for managing and treating laryngopharyngeal reflux disease (LPRD) to guide primary care and specialist physicians.
Methods: Twenty-three European experts (otolaryngologists, gastroenterologists, surgeons) participated in a modified Delphi process to revise 38 statements about the definition, clinical management, and treatment of LPRD. Three voting rounds were conducted on a 5-point scale and a consensus was defined a priori as agreement by 80% of the experts.
PLoS Pathog
December 2024
Institute of Human Genetics, School of Medicine, University Bonn & University Hospital Bonn, Bonn, Germany.
Courses of SARS-CoV-2 infections are highly variable, ranging from asymptomatic to lethal COVID-19. Though research has shown that host genetic factors contribute to this variability, cohort-based joint analyses of variants from the entire allelic spectrum in individuals with confirmed SARS-CoV-2 infections are still lacking. Here, we present the results of whole genome sequencing in 1,220 mainly vaccine-naïve individuals with confirmed SARS-CoV-2 infection, including 827 hospitalized COVID-19 cases.
View Article and Find Full Text PDFFront Pediatr
November 2024
Friede Springer Endowed Professorship for Global Child Health, Department of Medicine, Faculty of Health, Witten/Herdecke University, Witten, Germany.
Paediatric primary care is more frequently provided both by physicians other than specialised paediatricians as well as non-physician cadres in Europe and globally. The quality of paediatric primary care including a focus on preventive measures is rather variable and often does not comply with agreed international standards. WHO Europe developed standards for paediatric primary care applicable to the WHO Europe region and globally to improve the provision and outcome of paediatric primary care across all settings.
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