Biofilm formation in living organisms is associated to tissue and implant infections, and it has also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm development and being able to mimic such processes is vital for the successful development of antibiofilm treatments and therapies. Several decades of research have contributed to building the foundation for developing and biofilm models. However, no such thing as an "all fit" or biofilm models is currently available. In this review, in addition to presenting an updated overview of biofilm formation, we critically revise recent approaches for the improvement of and biofilm models.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113887PMC
http://dx.doi.org/10.1016/j.isci.2021.102443DOI Listing

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