AI Article Synopsis
- Eukaryotic organisms often have more DNA than you'd expect based on their complexity, leading to theories that this excess might have benefits despite not holding more genetic information.
- In a study of the rotifer species Brachionus asplanchnoidis, researchers found that larger genome sizes were linked to larger body sizes, bigger eggs, and longer embryonic development times.
- The findings suggest that natural selection can influence genome size in this population, although the effects must be significant enough to outweigh random genetic changes.
Article Abstract
Eukaryotic organisms usually contain much more genomic DNA than expected from their biological complexity. In explaining this pattern, selection-based hypotheses suggest that genome size evolves through selection acting on correlated life history traits, implicitly assuming the existence of phenotypic effects of (extra) genomic DNA that are independent of its information content. Here, we present conclusive evidence of such phenotypic effects within a well-mixed natural population that shows heritable variation in genome size. We found that genome size is positively correlated with body size, egg size, and embryonic development time in a population of the monogonont rotifer Brachionus asplanchnoidis. The effect on embryonic development time was mediated partly by an indirect effect (via egg size), and a direct effect, the latter indicating an increased replication cost of the larger amounts of DNA during mitosis. Our results suggest that selection-based change of genome size can operate in this population, provided it is strong enough to overcome drift or mutational change of genome size.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134563 | PMC |
| http://dx.doi.org/10.1038/s42003-021-02131-z | DOI Listing |
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