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http://dx.doi.org/10.1097/IOP.0000000000001726 | DOI Listing |
Arch Dermatol Res
December 2024
Dermatology, Venereology and Andrology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
With aging, facial lines on the forehead and glabella are sometimes converted from dynamic to static giving an aged appearance. Polydioxanone sutures are popular now as a management option in correcting deep static wrinkles on the upper face .This work was conducted to assess the synergistic efficacy of combining Botulinum toxin injection with Polydioxanone threads on the upper face static wrinkles.
View Article and Find Full Text PDFJ Headache Pain
December 2024
Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.
Combination treatments for migraine prophylaxis present a promising approach to addressing the diverse and complex mechanisms underlying migraine. This review explores the potential of combining oral conventional prophylactics, onabotulinumtoxin A, monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) pathway, and small molecule CGRP receptor antagonists (gepants). Among the most promising strategies, dual CGRP inhibition through mAbs and gepants may enhance efficacy by targeting both the CGRP peptide and its receptor, while the combination of onabotulinumtoxin A with CGRP treatments offers synergistic pain relief.
View Article and Find Full Text PDFCureus
November 2024
Institute of Minimal Access, Metabolic and Bariatric Surgery (iMAS), Sir Gangaram Hospital, New Delhi, IND.
The management of patients with open abdomen (OA) has long been a frustrating problem for surgeons, with high morbidity and mortality. OA secondary to laparotomy for septic peritonitis (one of the commonest causes) requires the control of abdominal wall retraction, prevention of evisceration and bowel fistulae, and overall control of infection. We present here the successful implementation of a relatively novel therapeutic combination of three different modern interventions on a 68-year-old patient with an open abdomen caused by an anastomotic leak following the reversal of Hartmann's operation.
View Article and Find Full Text PDFJ Bodyw Mov Ther
October 2024
Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkiye.
Purpose: This study aimed to investigate the effect of interventions applied in addition to Botulinum Toxin Type A (BoNT-A) application to the upper extremities on activity and participation in children with Cerebral Palsy (CP).
Materials And Methods: A systematic review was performed using the American Academy of Cerebral Palsy and Developmental Medicine Methodology. The PubMed, PEDro, ScienceDirect, Web of Science, and Cochrane Library databases were searched.
J Pharm Technol
November 2024
Lawson Research Institute, St. Joseph's Health Care London, London, ON, Canada.
To characterize randomized controlled trials (RCTs) of pharmacological interventions (prescription medications, nonprescription medications, and supplements) for the management of moderate to severe traumatic brain injury (MSTBI). Systematic searches were conducted in MEDLINE, PubMed, Scopus, CINAHL, EMBASE, and PsycINFO for RCTs up to December 2022 inclusive in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Inclusion criteria were RCT study design; participants' mean age ≥ 18 years and ≥ 50% had MSTBI; examined ≥ 1 pharmacological intervention(s), either alone or in combination with other interventions.
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