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A Hypercalcemic Crisis Complicating Subcutaneous Fat Necrosis of the Newborn: A Case Report and Literature Review.
Cureus
July 2024
Pediatric Nephrology, Mansoura University Children Hospital, Mansoura, EGY.
Article Synopsis
- Subcutaneous fat necrosis of the newborn (SFNN) is a rare skin condition that results in skin nodules and usually resolves on its own, but requires careful monitoring for complications like hypercalcemia.* -
- A case study described a male newborn who had two NICU admissions for hypoglycemia and sepsis, where reddish nodules appeared, leading to further health issues like hypercalcemia and eosinophilia.* -
- The infant developed complications including nephrocalcinosis and deep venous thrombosis, underscoring the need for ongoing observation of SFNN to identify any emerging health risks.*
Subcutaneous fat necrosis of the newborn: A systematic review of surgical management and outcomes.
J Plast Reconstr Aesthet Surg
April 2024
Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address:
Article Synopsis
- Subcutaneous fat necrosis of the newborn (SCFN) is a rare condition in neonates characterized by red plaques or nodules and may require surgical intervention in severe cases; however, there's limited literature on surgical outcomes.
- A systematic review identified 16 patients from 22 studies who underwent surgical management for SCFN, with the average age of diagnosis being about 12 days and surgery at around 40 days; common lesion locations were the back and limbs.
- The study found that conditions like therapeutic hypothermia were significant causes of SCFN, and more case reporting is needed to better understand surgical management and outcomes for affected patients.
Article Synopsis
- Sclerema neonatorum (SN) is a serious and rare skin condition found in newborns, characterized by the hardening of skin and fat tissue, primarily affecting sick, premature infants.
- The condition typically appears within the first week of life and is diagnosed clinically, with symptoms sparing areas without fat like palms and soles.
- In a case study, an eight-day-old premature infant with early-onset sepsis showed signs of SN but, despite treatment with antibiotics and topical creams, sadly passed away by day twelve.
Subcutaneous fat necrosis of the newborn: A retrospective study of 32 infants and care algorithm.
Pediatr Dermatol
May 2023
Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Article Synopsis
- The study focused on infants diagnosed with subcutaneous fat necrosis of the newborn (SCFN) at a children's hospital over a 10-year period, analyzing clinical and lab outcomes.
- Among the 32 infants, hypercalcemia was found in all cases, with some developing serious complications, including kidney issues, primarily within the first month of life.
- The findings suggest initial and ongoing monitoring of ionized calcium levels in SCFN cases, with specific care recommendations for infants exhibiting severe or prolonged hypercalcemia.
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