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Erring on the side of caution: Two failures to replicate the derring effect.
J Exp Psychol Gen
January 2025
Centre for Perception and Cognition, School of Psychology, University of Southampton.
It has been claimed that deliberately making errors while studying, even when the correct answers are provided, can enhance memory for the correct answers, a phenomenon termed the derring effect. Such deliberate erring has been shown to outperform other learning techniques, including copying and underlining, elaborative studying with concept mapping, and synonym generation. To date, however, the derring effect has only been demonstrated by a single group of researchers and in a single population of participants.
View Article and Find Full Text PDFLentivirus-mediated gene therapy for Fabry disease: 5-year End-of-Study results from the Canadian FACTs trial.
Clin Transl Med
January 2025
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Background: Fabry disease is an X-linked lysosomal storage disorder due to a deficiency of α-galactosidase A (α-gal A) activity. Our goal was to correct the enzyme deficiency in Fabry patients by transferring the cDNA for α-gal A into their CD34+ hematopoietic stem/progenitor cells (HSPCs). Overexpression of α-gal A leads to secretion of the hydrolase; which can be taken up and used by uncorrected bystander cells.
View Article and Find Full Text PDFThe Dual Dynamical Foundation of Orthodox Quantum Mechanics.
Stud Hist Philos Sci
December 2024
Department of Mathematics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany. Electronic address:
This paper combines mathematical, philosophical, and historical analyses in a comprehensive investigation of the dynamical foundations of the formalism of orthodox quantum mechanics. The results obtained include: (i) A deduction of the canonical commutation relations (CCR) from the tenets of Matrix Mechanics; (ii) A discussion of the meaning of Schrödinger's first derivation of the wave equation that not only improves on Joas and Lehner's 2009 investigation on the subject, but also demonstrates that the CCR follow of necessity from Schrödinger's first derivation of the wave equation, thus correcting the common misconception that the CCR were only posited by Schrödinger to pursue equivalence with Matrix Mechanics; (iii) A discussion of the mathematical facts and requirements involved in the equivalence of Matrix and Wave Mechanics that improves on F. A.
View Article and Find Full Text PDFSexual function after surgically corrected menstrual outflow obstruction due to congenital anomalies.
Facts Views Vis Obgyn
December 2024
Objectives: To enhance evidence-based knowledge about sexual function and the prevalence of sexual dysfunction after surgical therapy for congenital anomalies with menstrual outflow obstruction.
Materials And Methods: In this long-term case-control study, all patients underwent surgical correction of an obstructive Müllerian anomaly between 1980 and 2013. At the start of the case-control study, patients were at least 18 years old and were two years post their initial operation.
Background: In 2022, OpenAI launched ChatGPT 3.5, which is now widely used in medical education, training, and research. Despite its valuable use for the generation of information, concerns persist about its authenticity and accuracy.
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