AI Article Synopsis
- - The COVID-19 pandemic emphasizes the critical demand for safe and effective vaccines due to its massive societal and economic disruptions.
- - Two mRNA vaccines have rapidly progressed through late-stage clinical trials and have shown promising results.
- - The review discusses important aspects of mRNA vaccine development, new findings from ongoing clinical trials, and potential challenges ahead for these vaccines.
Article Abstract
The ongoing COVID-19 pandemic and its unprecedented global societal and economic disruptive impact highlight the urgent need for safe and effective vaccines. Taking substantial advantages of versatility and rapid development, two mRNA vaccines against COVID-19 have completed late-stage clinical assessment at an unprecedented speed and reported positive results. In this review, we outline keynotes in mRNA vaccine development, discuss recently published data on COVID-19 mRNA vaccine candidates, focusing on those in clinical trials and analyze future potential challenges.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959685 | PMC |
| http://dx.doi.org/10.1016/j.jgg.2021.02.006 | DOI Listing |
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