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A case of peribronchiolar metaplasia of the lung appearing as a solid nodule on computed tomography.
Nagoya J Med Sci
November 2024
Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Peribronchiolar metaplasia is an uncommon lesion characterized by fibrosis and bronchiolar epithelial cell proliferation along the peribronchiolar alveolar walls, primarily in response to bronchiolar and peribronchiolar injuries. Peribronchiolar metaplasia usually appears as ground glass nodules or sub-solid nodules on computed tomography. However, we present an exceptional case of peribronchiolar metaplasia that appeared as a solitary solid nodule on computed tomography.
View Article and Find Full Text PDFNon-metastatic causes of multiple pulmonary nodules.
Insights Imaging
November 2024
Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Article Synopsis
- Multiple pulmonary nodules can arise from either benign or malignant processes, with metastasis being a primary concern in patients with a known primary cancer.
- Differentiating between the causes of these nodules is complicated, as metastatic nodules can resemble those from infections, inflammation, and rare benign diseases.
- Radiological features, along with clinical and laboratory findings, play a crucial role in distinguishing between metastatic and non-metastatic causes of multiple pulmonary nodules, which is essential for accurate diagnosis and treatment.
Growth and Clinical Impact of Subsolid Lung Nodules ≥6 mm During Long-Term Follow-Up After Five Years of Stability.
Korean J Radiol
December 2024
Department of Radiology, Seoul National University Hospital, Seoul, Republic of Korea.
Article Synopsis
- - The study focused on analyzing the occurrence and timing of growth in subsolid nodules (SSNs) that had been stable for five years, investigating their clinical significance and determining an effective follow-up strategy.
- - Out of 235 SSNs followed for up to 181 months after initial stability, only 14 (6.0%) showed growth, and no metastases were found, indicating a very low growth incidence.
- - The proposed follow-up with CT scans every five years post-initial stability could effectively detect most of the growing nodules and any clinical stage shifts.
Prediction of the stage shift growth of early-stage lung adenocarcinomas by volume-doubling time.
Quant Imaging Med Surg
June 2024
Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung.
Background: Prediction of subsolid nodule (SSN) interval growth is crucial for clinical management and decision making in lung cancer screening program. To the best of our knowledge, no study has investigated whether volume doubling time (VDT) is an independent factor for predicting SSN interval growth, or whether its predictive power is better than that of traditional semantic methods, such as nodular diameter or type. This study aimed to investigate whether VDT could provide added value in predicting the long-term natural course of SSNs (<3 cm) regarding stage shift.
View Article and Find Full Text PDF[Value of peripheral blood rare cell EGFR gene amplification detection in the evaluation of benign and malignant pulmonary nodules].
Zhonghua Yi Xue Za Zhi
May 2024
Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100005, China.
To explore the value of detection of epidermal growth factor receptor (EGFR) gene amplification in peripheral blood rare cells in the assessment of benign and malignant pulmonary nodules. A total of 262 patients with pulmonary nodules were selected as the retrospectively study subjects from the Second Affiliated Hospital of Army Military Medical University and Peking Union Medical College Hospital from July 2022 to August 2023. There were 98 males and 164 females, with the age range from 16 to 79 (52.
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