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Prevalence and factors associated with teenage pregnancy in refugee settlements of northern Uganda post-COVID-19 (2020-2023): a cross-sectional study.
BMJ Open
December 2024
Reproductive Health, Gulu University, Gulu, Uganda.
Background: Following the COVID-19 pandemic, there was an increase in teenage pregnancies nationally, however, limited data exists regarding the same among girls living in refugee settlements.
Objectives: We evaluated the prevalence of teenage pregnancy and associated factors in Palorinya and Bidi Bidi refugee settlements in Obongi and Yumbe districts of northern Uganda, in the post-COVID-19 era.
Design: We conducted a cross-sectional study.
Long-term multi-systemic complications following SARS-CoV-2 Omicron and Delta infection in children: a retrospective cohort study.
Clin Microbiol Infect
December 2024
National Centre for Infectious Diseases, Singapore; Duke-NUS Graduate Medical School, National University of Singapore, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; Ministry of Health, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
Objectives: Most studies on long-term sequelae of SARS-CoV-2-infection in children were conducted pre-Omicron and pre-dated vaccination rollout. We examined long-term risk of new-incident multi-systemic sequelae after SARS-CoV-2 Delta/Omicron infection in a multi-ethnic Asian pediatric population.
Methods: Retrospective cohort study of Singaporean children aged 1- 17 years infected during Delta/Omicron BA.
Impact of Coronavirus Disease 2019 Emergency Declarations on Surgeries for Deep Neck Infection Incidence in Japan.
J Infect Chemother
December 2024
Department of Otolaryngology-Head and Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Introduction: Deep neck infections are lethal diseases; however, factors related to their prevention remain unclear. The national emergency declaration in April 2020, in response to COVID-19, spurred widespread adoption of nonpharmaceutical interventions (NPIs) such as hand washing, mask wearing, and social distancing.
Methods: This retrospective cohort study examines the impact of these interventions on the incidence of deep neck infections in Japan through interrupted time series analysis using National Database of Health Insurance Claims and Specific Health Checkups of Japan Open Data.
Pre-to-post COVID-19 pandemic trends in time from emergency department arrival to inpatient floor arrival: Door to floor time.
Am J Emerg Med
December 2024
Department of Internal Medicine (Section of General Internal Medicine, Program for Hospital Medicine), Yale University School of Medicine, New Haven, CT, USA; Department of Pediatrics (Section of Hospital Medicine), Yale University School of Medicine, New Haven, CT, USA.
Boarding of admitted patients in the Emergency Department (ED) changes both the setting and teams providing care during the initial phase of admissions. We measured the waiting time from ED door arrival to inpatient floor arrival for 17,944 admissions to internal medicine services over a 5-year period from 2018 to 2023 and propose this as a metric for the total delay in care associated with ED boarding, termed "Door to Floor" (DTF) time. We find a sustained increase as well as significant seasonal and day-of-the-week variation in DTF times.
View Article and Find Full Text PDFSafety of baricitinib in vaccinated patients with severe and critical COVID-19 sub study of the randomised Bari-SolidAct trial.
EBioMedicine
December 2024
Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Section for Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, Oslo, Norway. Electronic address:
Background: The Bari-SolidAct randomized controlled trial compared baricitinib with placebo in patients with severe COVID-19. A post hoc analysis revealed a higher incidence of serious adverse events (SAEs) among SARS-CoV-2-vaccinated participants who had received baricitinib. This sub-study aimed to investigate whether vaccination influences the safety profile of baricitinib in patients with severe COVID-19.
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