Mucorales infections in cetaceans have a high mortality rate. This case report refers to a bottlenose dolphin calf with suspected mucormycosis treated with posaconazole. This antifungal agent was discontinued after 96 days of therapy, however, the infection relapsed. Posaconazole was then resumed for a total of 255 days, with no signs of disease reactivation. The retrospective analysis of posaconazole serum levels in this successful case showed concentrations varying between 5.18 and 11.63 mg/L.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102706 | PMC |
| http://dx.doi.org/10.1016/j.mmcr.2021.04.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Introduction Mucormycosis is an uncommon fungal infection caused by filamentous fungi of the Mucorales order, namely Rhizopus, Lichthemia, andMucor species. The incidence and prevalence of mucormycosis reached an all-time high during the COVID-19 pandemic due to excessive steroid use and other factors, leading to the coining of the term CAM (COVID Associated Mucormycosis). The diagnosis of mucormycosis is by a combination of histopathology and microbiological techniques, such as KOH mount and culture.
View Article and Find Full Text PDFA rare intestinal mucormycosis caused by in a patient with diabetes: a case report.
Front Med (Lausanne)
October 2024
Department of Clinical Laboratory, The Affiliated Tai'an City Central Hospital of Qingdao University, Tai'an, Shandong, China.
Mucormycosis is an aggressive fungal disease. Gastrointestinal mucormycosis is rare, but its clinical symptoms lack specificity and mortality is high. Here, we report a case of intestinal mucormycosis caused by in a 65-year-old woman with diabetes mellitus.
View Article and Find Full Text PDFIntroduction: Real-world data from multinational observational studies are required to better understand the role and performance of isavuconazole in real-world practice in Europe.
Methods: A retrospective medical record review was conducted at 16 sites in Europe (France, Germany, Italy, Spain, and the United Kingdom). Eligible records were from patients aged ≥ 18 years at the time of isavuconazole initiation and received at least one dose of isavuconazole for suspected or confirmed invasive aspergillosis (IA) or invasive mucormycosis (IM) during the eligibility period (October 15, 2015 to June 30, 2019).
A case report: Comorbidity of Rhinocerebral mucormycosis and pulmonary aspergillosis with challenging diagnosis.
Front Med (Lausanne)
September 2024
Department of Otolaryngology, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China.
Article Synopsis
- - Mucormycosis, specifically rhinocerebral mucormycosis (RCM), is a rare and serious fungal infection that is often difficult to diagnose, leading to high mortality rates due to delays.
- - A case study highlighted a patient with both pulmonary aspergillosis and RCM, where the diagnosis was confirmed through advanced metagenomic Next-Generation Sequencing (mNGS), but despite aggressive treatment, the patient died.
- - The study concludes that early and accurate diagnosis of RCM is crucial due to its rapid progression, and mNGS can be particularly useful when traditional testing methods fail to identify the infection.
ISCCM Position Statement on the Management of Invasive Fungal Infections in the Intensive Care Unit.
Indian J Crit Care Med
August 2024
Department of Critical Care Medicine, ARETE Hospitals, Hyderabad, Telangana, India.
Rationale: Invasive fungal infections (IFI) in the intensive care unit (ICU) are an emerging problem owing to the use of broad-spectrum antibiotics, immunosuppressive agents, and frequency of indwelling catheters. Timely diagnosis which is imperative to improve outcomes can be challenging. This position statement is aimed at understanding risk factors, providing a rational diagnostic approach, and guiding clinicians to optimize antifungal therapy.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!