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http://dx.doi.org/10.1007/s13193-021-01305-9 | DOI Listing |
Dermatopathology (Basel)
December 2024
Arkadi M. Rywlin M.D. Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
PRAME (PReferentially expressed Antigen in MElanoma) is a tumor-associated antigen first identified in tumor-reactive T-cell clones derived from a patient with metastatic melanoma. Immunohistochemistry (IHC) for PRAME is useful for diagnostic purposes to support a suspected diagnosis of melanoma. Anecdotally, PRAME has been observed to stain sebaceous units in glands in background skin.
View Article and Find Full Text PDFJ Ethnopharmacol
December 2024
Experimental Research Center, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address:
Ethnopharmacological Relevance: Acne vulgaris is a common skin disease affecting the pilosebaceous unit, in which abnormal sebum secretion and inflammation play crucial roles. The traditional Chinese medicine Tanreqing has been utilized in dermatology to effectively treat various diseases. However, its effects and underlying mechanisms in acne vulgaris remain unclear.
View Article and Find Full Text PDFEye (Lond)
December 2024
Department of Ophthalmology, Bangalore Medical College and Research Institute, Bengaluru, India.
Background: The lacrimal caruncle, a nodular structure located at the inner canthus, contains a variety of tissue types, leading to diverse clinical manifestations of its lesions. Caruncular lesions, though rare, may be benign or malignant, complicating diagnosis and treatment. This systematic review aims to provide a comprehensive overview of the clinical profiles, histopathological features, and management strategies for caruncular lesions.
View Article and Find Full Text PDFInt J Surg Case Rep
December 2024
Department of Obstetrics and Gynecology, College of Medicine, King Khalid University, Saudi Arabia. Electronic address:
Introduction And Importance: Female circumcision, also known as female genital mutilation/cutting (FGM/C), is a common practice in many Arab countries, including Egypt. One potential complication of FGM/C is the development of a clitoral epidermal inclusion cyst, which occurs when keratinized epithelial cells and sebaceous glands become incorporated into the circumcision scar line in the clitoral or labial area. The objective of this study is to present a rare case of a large clitoral epidermal inclusion cyst following FGM/C and to review the current practice of FGM/C in the Arab world, including Egypt, Sudan, and Saudi Arabia.
View Article and Find Full Text PDFIran J Pathol
July 2024
Department of Dermatology, Pathology and Stem Cells Research Center, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Background & Objective: FFA usually has a gradual subtle course and might be overlooked by physicians or misdiagnosed with other types of hair loss including androgenetic alopecia, traction alopecia, and other types of patterned alopecia. In this study, we described clinicopathological features of patients with FFA referring for skin biopsy.
Methods: This is a retrospective cross-sectional study on 26 patients with a diagnosis of FFA based on clinicopathological features.
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