A 66-year female presented to the outpatient department (Medicine) of a tertiary care hospital with history of a recurrent sinus with multiple openings after a laparoscopic cholecystectomy surgery one and half years back. The excised tissue from sinus was sent for histopathology showed multiple non-caseating granulomas and was cultured for Mycobacterium. The growth from culture was identified as Mycobacterium mageritense by Line probe assay (LPA). The wound healed after ofloxacin and doxycycline was given for a period of two months. This case focuses the importance of proper diagnosis and treatment of chronic surgical infections keeping in mind the NTM.
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http://dx.doi.org/10.1016/j.ijmmb.2021.04.008 | DOI Listing |
J Clin Microbiol
December 2024
Laboratoire de Bactériologie, CHU Bordeaux, Bordeaux, France.
Accurate identification of non-tuberculous mycobacterial (NTM) species is crucial for the diagnosis and appropriate management of NTM infections. This study aimed to evaluate the performance of two assays, FluoroType Mycobacteria VER 1.0 and Maldi BioTyper (MBT) Mycobacteria.
View Article and Find Full Text PDFMicroorganisms
June 2024
Division of Immunology, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
The Esx-1 family proteins of the Type VII secretion systems of and have been assessed and are frequently used as candidates for tuberculosis (TB) diagnosis in both humans and animals. The presence of ESAT-6 and CFP 10 proteins, which are the most immunogenic proteins of the Esx-1 system and have been widely investigated for the immunodiagnosis of tuberculosis, in some and in , poses limitations for their use in specific diagnoses of TB. As such, to improve the specificity of the ESAT-6/CFP 10-based cell-mediated immunity (CMI) assays, other proteins encoded by genes within and outside the RD 1 region of the esx-1 locus have been evaluated as candidate antigens for CMI, as well as to investigate humoral responses in combination with ESAT-6 and or CFP 10, with varying specificity and sensitivity results.
View Article and Find Full Text PDFSAGE Open Med Case Rep
February 2024
Division of Infectious Diseases and Travel Medicine, Department of Medicine, Mount Auburn Hospital, Cambridge, MA, USA.
We herein report an unusual case of pacemaker infection at generator site in a 62-year old female with no pertinent past medical history. Pacemaker-related infections caused by nontuberculous mycobacteria are rare but can lead to significant morbidity and mortality. is rarely reported in pacemaker infections and is challenging to treat due to resistance to many antimicrobial agents.
View Article and Find Full Text PDFJ Infect Chemother
August 2024
Department of Plastic and Reconstructive Surgery, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi, 464-8681, Japan.
Mycobacterium mageritense (M. mageritense), a nontuberculous mycobacterium, is classified as a rapidly growing mycobacterium, class IV in the Runyon Classification. This bacterium is found in soil, water, and other habitats.
View Article and Find Full Text PDFMicrobiol Resour Announc
October 2023
Department of Systems Innovation, Graduate School of Engineering, University of Tokyo, Tokyo, Japan.
We report the complete genome of strain H4_3_1, which was isolated from a reactor of a hybrid biological-inorganic system. This genome will provide useful information about hydrogen-oxidizing bacteria as well as mycolicibacteria in non-host environments.
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