AI Article Synopsis
- A new method for making vinyloxyimidazopyridine compounds has been developed that doesn't use metals, using a one-pot reaction.
- The reaction combines 2-aminopyridine derivatives, arylglyoxal, and alkyne derivatives, all under the influence of a BF.OEt catalyst at room temperature.
- This process is notable for its simplicity, mild conditions, and the absence of transition metals, making it easier to handle and operate.
Article Abstract
A convenient and metal-free synthesis of vinyloxyimidazopyridine derivatives has been attained via BF.OEt promoted one-pot multicomponent approach. This procedure involves a facile coupling of 2-aminopyridine derivatives with arylglyoxal and alkyne derivatives. BF.OEt complexation has successfully catalyzed the reaction at room temperature. Utilization of transition metal-free catalyst, mild reaction conditions, easy handling and operational simplicity are key features of developed process.
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| http://dx.doi.org/10.1007/s11030-021-10228-0 | DOI Listing |
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