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| http://dx.doi.org/10.1016/j.jaclp.2021.04.003 | DOI Listing |
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Intravenous ketamine successfully treats treatment-resistant catatonia in schizophrenia: A case report.
Pharmacotherapy
October 2024
Houston Methodist Hospital, Houston, Texas, USA.
Article Synopsis
- Benzodiazepines and ECT are primary treatments for catatonia, which can arise from psychiatric or medical conditions, but when they're ineffective, ketamine has been explored as an alternative therapy.
- A case study highlighted a 77-year-old woman with treatment-resistant catatonia due to schizophrenia, who showed a rapid recovery after a single ketamine infusion when ECT was unavailable during the pandemic.
- While ketamine may be a promising option for drug-resistant catatonia, it needs to be used carefully because it could potentially worsen psychosis in patients with schizophrenia, indicating the need for more research in this area.
Catatonia responsive to corticosteroids in a patient with an SCN2A variant.
Am J Med Genet C Semin Med Genet
December 2024
Division of Child & Adolescent Psychiatry, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Variants in SCN2A are a known risk factor for developing autism spectrum disorder (ASD). Catatonia is a complex neuropsychiatric syndrome, which occurs at a higher rate in individuals with ASD. Catatonia has also been associated with COVID-19 infection, though the majority of these cases are associated with increased serum inflammatory markers.
View Article and Find Full Text PDFNew-onset schizophrenia in an adolescent after COVID-19.
J Nippon Med Sch
June 2024
Department of Neuropsychiatry, Nippon Medical School Musashi Kosugi Hospital.
Schizophrenia develops during adolescence. Maternal infections during the fetal period increase the incidence of schizophrenia in children, which suggests that the pathogenesis involves neuroinflammation. Here, we report a case of new-onset schizophrenia in a 16-year-old boy after COVID-19.
View Article and Find Full Text PDFSuccessful Treatment of Both Refractory Neuroleptic Malignant Syndrome and Subsequent Catatonia With Electroconvulsive Therapy in a Patient With Suspected Kufs Disease.
J ECT
June 2024
Old Age Psychiatry Service, Department of Psychiatry, Lausanne University Hospital (CHUV), University of Lausanne, Lausanne, Switzerland.
We describe a patient suffering from probable Kufs disease who developed a neuroleptic malignant syndrome (NMS) after use of an antipsychotic agent over some weeks during hospitalization due to neuropsychiatric symptoms. Transferred to the neurology department, the patient quickly developed catatonic features. She did not respond to usual medical treatment but did respond to electroconvulsive therapy (ECT).
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