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Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury: The TRAIN Randomized Clinical Trial.
JAMA
November 2024
Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
Importance: Blood transfusions are commonly administered to patients with acute brain injury. The optimal hemoglobin transfusion threshold is uncertain in this patient population.
Objective: To assess the impact on neurological outcome of 2 different hemoglobin thresholds to guide red blood cell transfusions in patients with acute brain injury.
Solving the "last mile" problem in overdose prevention: Lessons from the HEALing Communities Study.
Drug Alcohol Depend
November 2024
National Institute on Drug Abuse, Office of the Director, Gaithersburg, MD, United States.
Article Synopsis
- The "last mile" in logistics is complicated and expensive, similar to challenges in public health services like addressing overdoses.
- The HEALing Communities Study (HCS) shows how involving local communities and people with real experiences can help find better solutions for overdose prevention.
- The study faced challenges like slow data and stigma, but lessons from delivery systems can help make overdose prevention more effective and fair for everyone.
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Université Paris Cité, Institut Cochin, Inserm U1016, Paris, France
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International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.
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