Background: Locomotive syndrome (LoS) is condition wherein mobility functions such as sit-to-stand or gait are declined due to locomotive organ impairment. The important risk factors for the LoS are ageing and physical factors. Physical factors significantly associated with dental status Aim: To investigate the relationships between teeth lost and locomotive syndrome.
Materials And Method: A cross sectional study was carried among (45-90 years) individuals by using Loco Check List. Factors related to demographics (age, sex) and number of teeth lost were assessed. Pearson's chi-square test, multiple logistic regression analysis were performed. p <0.05 was considered to be statistically significant.
Results: Out of 322 subjects, majority of subjects (58.7%) hadLoS.Locomotive syndrome was observed high significantly (78.0% P = 0.0000) among >60 years age group. Majority of the subjects with tooth loss more than 10 teeth (92.6%) had a locomotive syndrome followed by the subjects with tooth loss 1-10 teeth (52.1%). Multiple logistic regression analysis revealed Locomotive syndrome was significantly (P= 0.000) higher among older age groups (>60 years) when compared with the 45- 60 years age group (or = 0.732) and subject with more than 10 teeth lost when compared with others (or = .009,or = 0.105) Conclusion: Study indicates that older age and number of teeth lost affect the prevalence of locomotive syndrome. Hence, maintaining oral health is necessary to retain more number of teeth throughout life which reduces the risk of locomotive syndrome.
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http://dx.doi.org/10.23750/abm.v92i2.9130 | DOI Listing |
Genes Brain Behav
February 2025
Laboratory of Addiction Genetics, Department of Pharmaceutical Sciences and Center for Drug Discovery, Northeastern University, Boston, Massachusetts, USA.
Opioid use disorder is heritable, yet its genetic etiology is largely unknown. C57BL/6J and C57BL/6NJ mouse substrains exhibit phenotypic diversity in the context of limited genetic diversity which together can facilitate genetic discovery. Here, we found C57BL/6NJ mice were less sensitive to oxycodone (OXY)-induced locomotor activation versus C57BL/6J mice in a conditioned place preference paradigm.
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November 2024
Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, Saga, Japan.
The 25-question Geriatric Locomotive Function Scale (GLFS-25) is a tool to identify locomotive syndrome, however, this tool is associated with the problem of a low complete response rate. We conducted this cross-sectional study of 2,474 community-dwelling residents to investigate the clinical characteristics of individuals who are prone to provide incomplete responses to the GLFS-25 questionnaire. The participants were divided into the following four groups based on the number of the GLFS-25 items they answered: 0 (n=279), 1-21 (n=36), 22-24 (n=273), and 25 (n=1,886).
View Article and Find Full Text PDFCureus
January 2025
Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima, JPN.
Purpose: Worsening sagittal alignment of the spine, particularly kyphosis, may cause difficulty in assuming a supine position, restricting sleeping posture and movement and potentially leading to sleep disturbances. However, no studies have explored the relationship between sagittal spinal alignment and sleep disturbance. This study aimed to clarify the relationship between sagittal spinal alignment and sleep disturbance.
View Article and Find Full Text PDFNat Commun
January 2025
Laboratory of Structural Biology of the Cell (BIOC), CNRS UMR7654, École Polytechnique, Institut Polytechnique de Paris, Palaiseau, France.
The molecular mechanisms underlying cell migration remain incompletely understood. Here, we show that knock-out cells for NHSL3, the most recently identified member of the Nance-Horan Syndrome family, are more persistent than parental cells in single cell migration, but that, in wound healing, follower cells are impaired in their ability to follow leader cells. The NHSL3 locus encodes several isoforms.
View Article and Find Full Text PDFArthrosc Tech
November 2024
iULS-University Institute for Locomotion and Sports, Hôpital Pasteur 2, University Côte d'Azur, Nice, France.
Chronic exertional compartment syndrome is a well-described potential cause of leg pain in high-level athletes and soldiers. Surgical treatment of chronic exertional compartment syndrome usually involves fasciotomy, with a reported rate of complications of up to 16%, including failure of complete compartmental release and delayed return to normal daily activity, which can take up to 6 to 12 weeks. The use of a minimally invasive approach under ultrasound guidance seems to improve clinical outcomes in young active patients.
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