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Efficacy of topical application of autologous platelet-rich plasma in adult tonsillectomy patients: a randomised control study. | LitMetric

AI Article Synopsis

  • * Participants were divided into two groups, with one receiving platelet-rich plasma treatment and the other not, followed by assessments for pain and healing over two weeks.
  • * Results showed a significant reduction in pain and faster healing in patients who received the platelet-rich plasma, indicating it could be a beneficial intervention post-surgery.

Article Abstract

Objective: Tonsillectomy is a painful surgery performed in cases of recurrent tonsillitis. Application of platelet-rich plasma to diminish the pain and morbidity post-tonsillectomy is gaining importance. This study evaluated post-operative pain and morbidity after autologous platelet-rich plasma application on the tonsil beds during tonsillectomy.

Method: Participants were randomised into group 1 (n = 28, peri-operative platelet-rich plasma intervention) and group 2 (n = 28, control). Post-tonsillectomy, patients were assessed (day 0, 1, 2, 3, 7 and 14) for pain, healing and time taken to return to normal activity. Data were analysed by independent t-test and chi-square test with p ≤ 0.05 as the significance level.

Results: A significant decrease in the mean pain score up to day 7 (p < 0.05) and tonsillar fossae healing on days 2 and 3 (p < 0.05) post-tonsillectomy was noted. The majority of the patients returned to their routine activities after a week post-tonsillectomy.

Conclusion: Platelet-rich plasma application was effective in accentuating healing and reducing post-tonsillectomy pain and morbidity.

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Source
http://dx.doi.org/10.1017/S0022215121000402DOI Listing

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