AI Article Synopsis
- Children and adolescents with cancer often receive treatment through a multidisciplinary approach, which includes radiotherapy for effective local control of tumors.
- However, traditional radiotherapy may lead to long-term side effects, such as second cancers and growth issues.
- Proton beam therapy (PBT) offers a safer alternative by targeting tumors while minimizing damage to surrounding healthy tissue, reducing risks of adverse outcomes in young patients; this document aims to outline PBT's benefits in treating pediatric and young adult cancer patients.
Article Abstract
Children and adolescents and young adults (AYAs) with cancer are often treated with a multidisciplinary approach. This includes use of radiotherapy, which is important for local control, but may also cause adverse events in the long term, including second cancer. The risks for limited growth and development, endocrine dysfunction, reduced fertility and second cancer in children and AYAs are reduced by proton beam therapy (PBT), which has a dose distribution that decreases irradiation of normal organs while still targeting the tumor. To define the outcomes and characteristics of PBT in cancer treatment in pediatric and AYA patients, this document was developed by the Japanese Society for Radiation Oncology (JASTRO) and the Japanese Society of Pediatric Hematology/Oncology (JSPHO).
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| http://dx.doi.org/10.1016/j.ctrv.2021.102209 | DOI Listing |
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