Complications of laser hair reduction should be classified not only to skin and ocular complications but to skin, ocular, and scalp hair complications. Do not forget the plumes. Awareness about laser dangers is very critical. In this way, able to progress the security of both patients and laser providers. Does Nd: YAG cause more bad effect than Alexandrite on scalp hair melanin of laser providers and why? The study aimed at detecting the effect of cumulative exposure to scattered beam during laser hair reduction on the laser providers which may cause unexpected scalp hair melanin affection. The study included 150 female subjects: One hundred medical personnel engaged in laser-assisted hair reduction procedure; half of them were wearing head cover (hijab) and 50 female subjects not dealing with hair reduction laser systems (half of them were wearing hijab). Two laser devices were used: Alexandrite laser (GentleLase PRO® 755 nm, Candela Corp., Wayland, MA, USA) and neodymium-doped Yttrium Aluminium Garnet (Nd: YAG) (Synchro HP 1064 nm, Deka M.E.L.A s.r.l., Calenzano (FI), Italy) laser. A significant higher number of grey hairs in medical personnel (P < 0.001) was evident at the initial examination and at each follow-up visit thereafter. The number of grey hairs at initial assessment, after 6 months and after 1 year, was significantly higher in medical personnel dealing with Nd: YAG laser than those using long-pulsed Alexanderite laser (P < 0.001 each). A noteworthy positive correlation was found between working years, grey hair number at the start of study, and the progression (excess) in number of grey hairs after 1 year regardless of the laser system used. It seems that scalp hair pigment needs specific protection as does the eye pigment. Greater attention should be paid to possible long-term hazards particularly on service providers.
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http://dx.doi.org/10.1007/s10103-021-03334-w | DOI Listing |
Mutations in the gene cause the most common form of human hereditary hearing loss, known as DFNB1. is expressed in two cell groups of the cochlea-epithelial cells of the organ of Corti and fibrocytes of the inner sulcus and lateral wall-but not by sensory hair cells or neurons. Attempts to treat mouse models of DFNB1 with AAV vectors mediating nonspecific expression have not substantially restored function, perhaps because inappropriate expression in hair cells and neurons could compromise their electrical activity.
View Article and Find Full Text PDFPregnancy is a period of profound biological transformation. However, we know remarkably little about pregnancy-related brain changes. To address this gap, we chart longitudinal changes in brain structure during pregnancy and explore potential mechanisms driving these changes.
View Article and Find Full Text PDFJ Drugs Dermatol
January 2025
Background: Exosomes are small extracellular vesicles (30-150 nm in size) that play a critical role in cellular communication, transporting proteins, lipids, and nucleic acids between cells. This literature review focuses on evaluating the potential benefits and limitations of exosomes in enhancing skin health and aesthetics through indications such as skin rejuvenation, hair restoration, and pigmentation disorders.
Methods: A thorough literature search was conducted on PubMed using specific MeSH, including "exosomes," "aesthetics," "cosmetic dermatology," "skin rejuvenation," "hair growth," and "wrinkle reduction.
SAGE Open Med Case Rep
January 2025
Division of Dermatology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Discoid lupus erythematosus is a chronic, recurring, autoimmune skin disease causing annular, scarring plaques on the head and neck. Deucravacitinib, a tyrosine kinase 2 inhibitor in the Janus kinase inhibitor family, represents an emerging treatment option in systemic lupus erythematosus with potential applicability to discoid lupus erythematosus. We describe a 48-year-old woman with multiple treatment-refractory scalp plaques and associated alopecia treated with deucravacitinib.
View Article and Find Full Text PDFInt J Cosmet Sci
January 2025
L'Oréal Research & Innovation, Aulnay-sous-Bois, France.
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