Individuals with overgrowth have been the subjects of numerous myths and art pieces in various cultures, often depicted as deities or creatures of divine origin, such as giants or titans. In more recent times, however, subjects with signs of generalized or segmental overgrowth have been considered as "freaks of nature," in the disparaging language of the time, and represented in artworks as elements of entertainment or amusement. The different meanings assigned to overgrowth in myth and art through time provide an interesting perspective of the sociocultural approach to dysmorphic traits and genetic disorders.
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[SIBO, from myth to reality].
Rev Med Interne
January 2025
Service de médecine interne et maladie infectieuse, hôpital européen, 6, rue Désirée-Clary, 13003 Marseille, France; Service de recherche clinique, laboratoire européen Alphabio Biogroup, Marseille, France.
Digestive functional disorders are among the most frequent reasons for medical consultation and a significant source of medical wandering. Therapeutic management of these patients is difficult, particularly due to the absence of specific treatment linked to an incomplete understanding of the pathophysiological mechanisms. In a certain number of these patients, the symptoms are accompanied by a small intestinal bacterial overgrowth (SIBO).
View Article and Find Full Text PDFThe true story of the "strong and gentle" Acciano's Giant.
Growth Horm IGF Res
April 2022
Department of Life, Health and Environmental Sciences, University of L'Aquila, Italy; Allergy and Clinical Immunology Unit, Center for the diagnosis and treatment of Osteoporosis, AUSL 04 Teramo, Italy.
This is the story of a giant who lived in Abruzzo 200 years ago. He became a symbol for his people and a strong resilience generator. Gigantism, in the history of humanity has always attracted attention, albeit passing over the centuries from myth, from divinity to the freak phenomenon, the freak of nature that becomes a spectacle to show off.
View Article and Find Full Text PDFOvergrowth in myth and art.
Am J Med Genet C Semin Med Genet
June 2021
JC Self Research Institute, Greenwood Genetic Center, Greenwood, South Carolina, USA.
Individuals with overgrowth have been the subjects of numerous myths and art pieces in various cultures, often depicted as deities or creatures of divine origin, such as giants or titans. In more recent times, however, subjects with signs of generalized or segmental overgrowth have been considered as "freaks of nature," in the disparaging language of the time, and represented in artworks as elements of entertainment or amusement. The different meanings assigned to overgrowth in myth and art through time provide an interesting perspective of the sociocultural approach to dysmorphic traits and genetic disorders.
View Article and Find Full Text PDFReported shoes size during GH therapy: is foot overgrowth a myth or reality?
Arch Endocrinol Metab
October 2015
Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, Santa Casa de São Paulo School of Medical Sciences, São Paulo, SP, Brazil.
Objectives: To describe population reference values for shoes size, and to identify possible disproportional foot growth during GH therapy.
Materials And Methods: Construction of percentile chart based on 3,651 controls (male: 1,838; female: 1,813). The GH treated group included 13 children with idiopathic short stature (ISS) and 50 children with normal height, but with height prediction below their target height; male: 26 and female: 37 mean ± SD age 13.
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