This study was to examine the patients with acute cerebral infarction (ACI) treated at a single center over 9 years and who underwent Unruptured intracranial aneurysm (UIA) screening by three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA), and to explore the factors associated with outcomes. The outcome was the modified Rankin scale (mRS) score at 90 days after stroke onset. The outcome was classified into a good outcome (mRS score of 0-2 points) and poor outcome (mRS score of 3-6 points). UIAs were found in 260 (6.5%) of 4,033 patients with ACI; 2,543 (63.1%) had a good outcome, and 1,490 (36.9%) had a poor outcome. There was no difference in outcomes between the two groups ( = 0.785). The multivariable analysis showed that age (OR = 1.009, 95%CI: 1.003-1.014, = 0.003), diabetes (OR = 1.179, 95%CI: 1.035-1.342, = 0.013), ischemic stroke history (OR = 1.451, 95%CI: 1.256-1.677, < 0.001), and baseline NIHSS score (OR = 1.034, 95%CI: 1.018-1.050, < 0.001) were independently associated with the 90-day outcomes in patients with ACI. The presence of incidental UIA was not associated with outcomes after ACI. Age, diabetes, ischemic stroke history, and baseline NIHSS score were independently associated with the early outcomes of patients with ACI.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107683PMC
http://dx.doi.org/10.3389/fneur.2021.613027DOI Listing

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