Background: The use of ionizing radiation during cardiac catheterization interventions adversely impacts the medical staff. Traditional radiation protection equipment is only partially effective. The Cathpax® radiation protection cabin (RPC) has proven to significantly reduce radiation exposure in electrophysiological and neuroradiology interventions. Our objective was to analyze whether the Cathpax® RPC reduces radiation dose in coronary and cardiac structural interventions in unselected real-world procedures.
Methods And Results: In this nonrandomized all-comers prospective study, 119 consecutive cardiac interventional procedures were alternatively divided into two groups: the RPC group (n = 59) and the non-RPC group (n = 60). No significant changes in the characteristics of patients and procedures, average contrast volume, air kerma (AK), dose area-product (DAP) and fluoroscopy time between both groups were apparent. In the RPC group, the first-operator relative radiation exposure was reduced by 78% at the chest and by 70% at the wrist. This effect was consistent during different types of procedures including complex percutaneous interventions and structural procedures.
Conclusions: Our study demonstrates, for the first time, that the Cathpax® cabin significantly and efficiently reduces relative operator radiation exposure during different types of interventional procedures, confirming its feasibility in a real-world setting.
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http://dx.doi.org/10.1002/ccd.29773 | DOI Listing |
EJNMMI Res
December 2024
μNEURO Research Centre of Excellence, Universiteitsplein 1, University of Antwerp, Antwerp, Belgium.
Background: Huntington's disease (HD) is a rare neurodegenerative disorder caused by an expansion of the CAG trinucleotide repeat in the huntingtin gene which encodes the mutant huntingtin protein (mHTT) that is associated with HD-related neuropathophysiology. Noninvasive visualization of mHTT aggregates in the brain, with positron emission tomography (PET), will allow to reliably evaluate the efficacy of therapeutic interventions in HD. This study aimed to assess the radiation burden of [F]CHDI-650, a novel fluorinated mHTT radioligand, in humans based on both in vivo and ex vivo biodistribution in mice and subsequent determination of dosimetry for dosing in humans.
View Article and Find Full Text PDFDysphagia
December 2024
Department of Otorhinolaryngology-Head and Neck Surgery, Rennes University Hospital, 2 Rue Henri Le Guilloux, Rennes CEDEX 9, 35033, France.
Videofluoroscopy, recognized as the gold standard for dysphagia exploration, has inherent limitations, including poor soft tissue discrimination, radiation exposure, and aspiration risk. In response to these challenges, cine-MRI of swallowing has evolved over the past three decades, yielding diverse methodologies and results across various studies.This systematic review, conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, meticulously outlines cine-MRI protocols, applications, advantages, and limitations.
View Article and Find Full Text PDFMetabolites
December 2024
College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
Volatile compounds have a deep influence on the quality and application of the medicinal herb ; however, little is known about the effect of UV-B radiation on volatile metabolites. We herein investigated the effects of UV-B exposure on the volatile compounds and transcriptome of to assess the potential for improving its quality and medicinal characteristics. Out of 733 volatiles obtained, a total of 133 differentially expressed metabolites (DEMs) were identified by metabolome analysis.
View Article and Find Full Text PDFBiomimetics (Basel)
December 2024
Institute of Knowledge Technology, University Complutense of Madrid, 28040 Madrid, Spain.
The COVID-19 pandemic highlighted the urgent need for effective surface disinfection solutions, which has led to the use of mobile robots equipped with ultraviolet (UVC) lamps as a promising technology. This study aims to optimize the navigation of differential mobile robots equipped with UVC lamps to ensure maximum efficiency in disinfecting complex environments. Bio-inspired metaheuristic algorithms such as the gazelle optimization algorithm, whale optimization algorithm, bat optimization algorithm, and particle swarm optimization are applied.
View Article and Find Full Text PDFWorld J Clin Cases
December 2024
Department of Medicine and Pharmacology, Texas A and M University, College Station, TX 77843, United States.
Assessing diaphragm function status is vital for diagnosing and treating acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Diaphrag-matic ultrasound has become increasingly important due to its non-invasive nature, absence of radiation exposure, widespread availability, prompt results, high accuracy, and repeatability at the bedside. The diaphragm is a crucial respiratory muscle.
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