In 18 ragweed hay fever patients who received injections of alum-precipitated pyridine (Allpyral) ragweed extracts in maintenance doses of between 6000 and 8000 P.N.U. at intervals of between two and four months over a two-year period, the prolonged interval did not seem to influence either the clinical response or the tendency to reaction, or result in significant change in immunological tolerance as determined by antibody studies, which included fluorescent antibody assays, as well as hemagglutination and RAST technics.
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Titration of immunotherapy by periodical nasal allergic challenges in the treatment of allergic rhinitis.
Med J Aust
July 1992
Royal Hobart Hospital, Qld., Australia.
Objective: To determine the benefits of nasal allergen challenge (NAC) in monitoring immunotherapy for allergic rhinitis in a clinical setting.
Design: Two hundred consecutive courses of immunotherapy, with pyridine-extracted alum-precipitated allergen extracts (Allpyral), were personally carried out by the writer and analysed. Diagnosis before treatment was confirmed by NAC and the duration of treatment determined by periodical NAC.
Improved diagnosis and treatment of allergic rhinitis by the use of nasal provocation tests.
Ann Allergy
January 1988
Royal Hobart Hospital, Tasmania, Australia.
A simple and safe method of nasal provocation for out-patients that requires no special equipment is described. A total of 2,645 cases were tested by nasal provocation tests. Of the total, 1,175 were tested with Dermatophagoides pteronyssinus, 825 with mixed grass pollens, 352 with plantain (Plantago lanceolata), and 125 for cats and correlating nasal tests with skin tests yielded 80%, 90%, and 85%, respectively.
View Article and Find Full Text PDFAllergenicity of alum-precipitated grass pollen extracts with different RAST activity.
Clin Allergy
September 1987
Medical Department TTA, State University Hospital, Copenhagen, Denmark.
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Allergol Immunopathol (Madr)
August 1987
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View Article and Find Full Text PDF[Comparison of 3 types of immunotherapy for treating grass pollen-induced allergic rhinitis].
Allerg Immunol (Paris)
September 1986
Centre de Recherche en Immunologie et Rhumatologie, Centre Hospitalier de l'Université Laval.
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