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Background/aims: Certain sociodemographic groups are routinely underrepresented in clinical trials, limiting generalisability. Here, we describe the extent to which enriched enrolment approaches yielded a diverse trial population enriched for older age in a randomised controlled trial of a blood-based multi-cancer early detection test (NCT05611632).
Methods: Participants aged 50-77 years were recruited from eight Cancer Alliance regions in England.
Data Fusion Applied to the Leader-Based Bat Algorithm to Improve the Localization of Mobile Robots.
Sensors (Basel)
January 2025
Department of Electrical Engineering, Universidade Federal do Espírito Santo, Vitória 29075-910, ES, Brazil.
The increasing demand for autonomous mobile robots in complex environments calls for efficient path-planning algorithms. Bio-inspired algorithms effectively address intricate optimization challenges, but their computational cost increases with the number of particles, which is great when implementing algorithms of high accuracy. To address such topics, this paper explores the application of the leader-based bat algorithm (LBBA), an enhancement of the traditional bat algorithm (BA).
View Article and Find Full Text PDFEffects of Different Nitrogen Fertilizer Application Rates on Soil Microbial Structure in Paddy Soil When Combined with Rice Straw Return.
Microorganisms
January 2025
Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education & Heilongjiang Provincial Key Laboratory of Ecological Restoration and Resource Utilization for Cold Region & Key Laboratory of Microbiology, College of Heilongjiang Province & School of Life Sciences, Heilongjiang University, Harbin 150080, China.
Metagenomic sequencing of the microbial soil community was used to assess the effect of various nitrogen fertilizer treatments in combination with constant rice straw return to the soil in the tiller layer of Northeast China's black paddy soil used for rice production. Here, we investigated changes in the composition, diversity, and structure of soil microbial communities in the soil treated with four amounts of nitrogen fertilizers (53, 93, 133, and 173 kg/ha) applied to the soil under a constant straw return of 7500 kg/ha, with a control not receiving N. The relationships between soil microbial community structure and soil physical and chemical properties were determined.
View Article and Find Full Text PDFTemperature-Responsive Hybrid Composite with Zero Temperature Coefficient of Resistance for Wearable Thermotherapy Pads.
Micromachines (Basel)
January 2025
Department of Mechanical Engineering, Soongsil University, 369 Sangdo-ro, Dongjak-Gu, Seoul 06978, Republic of Korea.
Carbon-based polymer composites are widely used in wearable devices due to their exceptional electrical conductivity and flexibility. However, their temperature-dependent resistance variations pose significant challenges to device safety and performance. A negative temperature coefficient (NTC) can lead to overcurrent risks, while a positive temperature coefficient (PTC) compromises accuracy.
View Article and Find Full Text PDFMetabolic Performance of Mealworms and Black Soldier Fly Larvae Reared on Food and Agricultural Waste and By-Products.
Animals (Basel)
January 2025
Department of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, DK-9220 Aalborg, Denmark.
Mealworms and black soldier fly (BSF) larvae are two of the most reared insects at an industrial scale. Both may feed on by-products from agricultural and food industries. Feed efficiency is one of the most important aspects of such processes and varies between species and feed substrates and depends on the metabolic performance of the larvae.
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