AI Article Synopsis

  • Structural biology is important in combating COVID-19 by helping us visualize and understand the SARS-CoV-2 virus.
  • The rapid determination of SARS-CoV-2 protein structures sometimes includes errors, which can complicate drug development.
  • The Coronavirus Structural Task Force is dedicated to improving these protein structures and making their findings accessible to the public through the website https://insidecorona.net/.

Article Abstract

Structural biology plays a crucial role in the fight against COVID-19, permitting us to ‘see’ and understand SARS-CoV-2. However, the macromolecular structures of SARS-CoV-2 proteins that were solved with great speed and urgency can contain errors that may hinder drug design. The Coronavirus Structural Task Force has been working behind the scenes to evaluate and improve these structures, making the results freely available at https://insidecorona.net/.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8340564PMC
http://dx.doi.org/10.1038/s41594-021-00593-7DOI Listing

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