AI Article Synopsis
- Many patients experiencing angina or signs of ischemic heart disease do not show obstructive coronary artery disease during angiography, indicating a condition called INOCA.
- Patients with INOCA often have a coronary vasomotor dysfunction, leading to recommendations for diagnostic testing to assess this issue.
- The article discusses a continuous thermodilution method for evaluating coronary blood flow and resistance, suggesting it may be more effective than standard physiological measures.
Article Abstract
In approximately half of the patients undergoing coronary angiography for angina pectoris or for signs or symptoms suggestive of ischemic heart disease, no obstructive coronary artery disease is angiographically visible. The majority of these patients with angina or ischemia and no obstructive coronary artery disease (INOCA) have an underlying coronary vasomotor dysfunction, and current consensus documents recommend diagnostic invasive coronary vasomotor function testing (CFT). During CFT, a variety of vasomotor dysfunction endotypes can be assessed, including vasospastic coronary dysfunction (epicardial or microvascular vasospasm), and/or microvascular vasodilatory dysfunction, including impaired vasodilatory capacity and increased microvascular resistance. The quantification of the continuous thermodilution derived absolute coronary blood flow and resistance might be a better measure compared to the currently used standard physiologic measures. This article provides an overview of this continuous thermodilution method.
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| http://dx.doi.org/10.3791/62066 | DOI Listing |
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