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The Effect of Denosumab on Pain and Radiological Improvement in Giant Cell Tumours of the Spine in the Acute Setting.
Global Spine J
January 2025
Department of Spinal Surgery, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Study Design: Retrospective Cohort Study.
Objectives: The current recommended treatment for Giant Cell Tumour (GCT) of the spine is en bloc excision. Denosumab is a monoclonal antibody reducing osteoclast activity that shows promising results when used as a neo - adjuvant treatment.
Delayed Development of a Giant Cranial Pseudomeningocele After Surgical Excision of a Parasagittal Meningioma: A Case Report.
Cureus
December 2024
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, IND.
Pseudomeningoceles are among the most common postoperative neurosurgical complications, usually presenting in the early postoperative period and often responding well to nonsurgical management. Here, we present a case of a giant cranial pseudomeningocele that developed three years after parasagittal meningioma resection, without any known risk factors. Despite conservative measures, the pseudomeningocele grew significantly over two years, reaching 22 cm along its long axis.
View Article and Find Full Text PDFAdolescent thoracic scoliosis due to giant ganglioneuroma: a two-case report and literature review.
Nagoya J Med Sci
November 2024
Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Ganglioneuromas are rare benign tumors that arise from the sympathetic nervous system. The presentation of tumors is variable and associated with adolescent thoracic scoliosis. Herein, we present two case reports and a review of literature.
View Article and Find Full Text PDFGiant Right Atrial Myxoma Coexisting With Tricuspid Regurgitation, Coronary Artery Disease, and Aortic Stenosis.
Cureus
December 2024
Cardiovascular and Thoracic Unit, Department of Surgery, Lampang Hospital, Lampang, THA.
A 70-year-old man presented to our hospital with chest discomfort and epigastric pain. Echocardiography revealed a giant atrial myxoma in the right atrium with severe tricuspid regurgitation. The aortic valve was calcified, and severe aortic stenosis was observed.
View Article and Find Full Text PDFExpression of α Integrin in Feline Injection-Site Sarcoma (FISS): Preliminary Investigations.
Animals (Basel)
December 2024
Department of Veterinary Medicine and Animal Sciences, University of Milan, 26900 Lodi, Italy.
Feline injection-site sarcomas (FISSs) are malignant skin tumors of mesenchymal origin arising at local post-vaccination (or injection) sites. In recent years, a fluorescence imaging technique based on probes targeting αβ integrin has been effectively applied for the surgical complete resection of the tumor. In our study, we investigated the utility of a commercially available anti-α integrin polyclonal antibody for the histopathological evaluation of FISS's surgical excision margins.
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