Grapes are known to synthesize resveratrol, a stilbene phytoalexin, associated with cancer chemopreventive activity and cardioprotection. The effect of ultrasound (US) abiotic elicitor treatments on trans-resveratrol content in Kalecik Karası fresh and frozen grape skin was determined. D-optimal point change design was used under RSM for the experimental design of US treatment. The optimization was solved with the help of the Pareto areas and the optimal input variable values were determined by the desirability function with fuzzy similar perceivable ratio method. The optimum conditions of US treatment for fresh grape skin were determined as follows: incubation time-24 h, US application method-(P01), US frequency-20 kHz, US treatment time-60 min and ultrasonic intensity (UI)-1.15 W cm. The trans-resveratrol content (0.18 ± 0.01 mg/g) in the untreated grape skin significantly increased with optimum US treatment (3.58 ± 0.08 mg/g), increasing production to 19.9 times.
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http://dx.doi.org/10.1007/s13197-020-04722-w | DOI Listing |
Pharmaceutics
January 2025
Faculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria.
Resveratrol is a natural polyphenol (stilbenoid), which can be found in grape skin, red wine, blueberries, peanuts and others. The biological properties of resveratrol, in particular antioxidant, anti-inflammatory, anticancer, estrogenic, vasorelaxant and cardioprotective activity, are the main reason for its importance in medicine and pharmacy. Despite all of its advantages, however, there are many problems related to this polyphenolic substance, such as low stability, water insolubility, poor bioavailability and fast metabolism.
View Article and Find Full Text PDFFood Chem
January 2025
National Engineering Research Center of Rice and Byproduct Deep Processing, College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, Hunan, China.
Oryzanol has a variety of physiological activities and is widely used in food and medicine. However, its utilization form and bioavailability are limited by poor solubility and photothermal stability. In this paper, an inclusion complex (IC) was prepared by modifying β-cyclodextrin as a molecular carrier to encapsulate Oryzanol.
View Article and Find Full Text PDFIndian J Clin Biochem
January 2025
Department of Biochemistry, College of Medicine and J.N.M Hospital, WBUHS, Kalyani, West Bengal 741235 India.
Radiation therapy uses ionizing radiation (IR) to kill cancer cells. However, during radiotherapy normal cells are also damaged and killed by the generation of reactive oxygen species. Polyphenolic compounds are known to mitigate the damaging effects of radiation.
View Article and Find Full Text PDFFood Chem
December 2024
Univ. Bordeaux, INRAE, Bordeaux INP, Bordeaux Sciences Agro, UMR 1366, OENO, ISVV, Villenave d'Ornon, F-33140, France.
A varietal origin of eugenol was previously demonstrated in Baco blanc, a major grapevine variety used to produce Armagnac wine spirits. Eugenol was found in high amount, both as the free and as unidentified glycosylated forms. To reveal their identity, a specific method was developed and applied to berry skin extracts.
View Article and Find Full Text PDFPlants (Basel)
December 2024
Key Laboratory of Ministry of Education for Genetics, Breeding and Multiple Utilization of Crops, College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Anthocyanins are responsible for grape ( L.) skin color. To obtain a more detailed understanding of the anthocyanin regulatory networks across' the summer and winter seasons in grapes under a double-cropping viticulture system, the transcriptomes of 'Summer Black' grapes were analyzed using RNA sequencing.
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