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CPAP Therapy for OSA and Its Impact on Various Cardiovascular Disorders.
Cardiol Rev
January 2025
Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan.
Obstructive sleep apnea (OSA), a highly prevalent and serious disorder with significant complications, causes considerable daytime and nighttime symptoms as well as long-term consequences and is yet an underdiagnosed and inadequately treated condition. Patients with OSA undergo frequent awakenings during the sleep cycle and find it impossible to get restorative sleep. Individuals are extremely fatigued, sleepy, and irritable throughout the day.
View Article and Find Full Text PDFExploring the therapeutic potential of GLP-1 receptor agonists in the management of obstructive sleep apnea: a comprehensive review.
J Basic Clin Physiol Pharmacol
January 2025
Pharmacology, MGM Medical College and Hospital, MGM Institute of Health Sciences, Nerul, Navi Mumbai, Maharashtra, India.
Obstructive Sleep Apnea (OSA) is a prevalent sleep disorder marked by repeated episodes of partial or complete upper airway obstruction during sleep, which leads to intermittent hypoxia and fragmented sleep. These disruptions negatively impact cardiovascular health, metabolic function, and overall quality of life. Obesity is a major modifiable risk factor for OSA, as it contributes to both anatomical and physiological mechanisms that increase the likelihood of airway collapse during sleep.
View Article and Find Full Text PDFTransoral Drug-Induced Sleep Endoscopy: A Useful Complementary Tool in Sleep Surgery.
Int Arch Otorhinolaryngol
January 2025
Department of Chest Diseases, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Drug-induced sleep endoscopy (DISE) is performed widely, and several studies have demonstrated its validity as it provides clinical information not available by routine clinical inspection alone. This study aims to evaluate the role of transoral drug-induced sleep endoscopy (DISE) in the evaluation of tongue-palate (TP) interaction and its impact on surgical outcomes. A total of 42 patients with known obstructive sleep apnea syndrome (OSAS) were classified into two groups according to TP interaction (the absence of space between tongue and palate with the visual impression that the tongue is pushing the soft palate) into +ve and -ve TP interaction.
View Article and Find Full Text PDFEffects of continuous positive airway pressure treatment on arterial stiffness and inflammatory factors in patients with coronary heart disease complicated with obstructive sleep apnea.
J Cardiothorac Surg
January 2025
Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Background: Continuous Positive Airway Pressure (CPAP) treatment brings more benefits than risks to most coronary heart disease (CHD) patients with obstructive sleep apnea (OSA). However, the pathophysiological mechanism by which CPAP treatment improves the prognosis of patients with CHD and OSA remains unclear. The purpose of this study was to clarify whether CPAP can improve arterial stiffness and inflammatory factor levels in CHD patients with OSA, and to further improve prognosis.
View Article and Find Full Text PDFThe Role of Rapid Maxillary Expansion in the Management of Obstructive Sleep Apnoea: Monitoring Respiratory Parameters-A Systematic Review and Meta-Analysis.
J Clin Med
December 2024
Department of Orthodontics, Faculty of Medicine and Health Science, Catholic University of Valencia, 46001 Valencia, Spain.
Obstructive sleep apnoea (OSA) is a sleep-related breathing condition that involves the presence of episodic disruptions to the sleeping pattern due to partial or complete airway obstruction. There are a range of treatment options that exist to alleviate the symptoms of this condition including CPAP, mandibular advancement, and maxillary expansion techniques. This systematic review and meta-analysis of published articles aims to determine if rapid maxillary expansion ("RME") is an effective treatment option in the management of OSA, using quantitative parameters of AHI and SpO.
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