Background: Enchondromas originating in the epiphyses of long bones are rare and epiphyseal osteoid osteomas are also uncommon. Diagnosis can become elusive when enchondromas or osteoid osteomas occur in atypical locations and present with nonspecific clinical and imaging characteristics.
Case Presentation: We report a case of epiphyseal enchondroma of the left proximal femur in a 15-year-old girl with a 2-month history of left lower extremity pain. Preoperative CT displayed thickened cortex in the anterior surface of the left proximal femur with specks of calcification and inhomogeneity of the adjacent bone marrow cavity. She was diagnosed with osteoid osteoma. Postoperative pathological examination of surgically excised specimens revealed a diagnosis of enchondromas.
Conclusions: Our case highlights that enchondroma should be considered in lesions of the epiphysis.
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http://dx.doi.org/10.1186/s40001-021-00504-y | DOI Listing |
Sci Rep
October 2024
Department of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Enchondromas are a common tumor in bone that can occur as multiple lesions in enchondromatosis, which is associated with deformity of the affected bone. These lesions harbor somatic mutations in IDH and driving expression of a mutant Idh1 in Col2 expressing cells in mice causes an enchondromatosis phenotype. Here we compared growth plates from E18.
View Article and Find Full Text PDFMedicine (Baltimore)
July 2024
Department of Radiology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Radiol Case Rep
July 2023
Department of Radiology, University of California Davis School of Medicine, 4860 Y St. Suite 3100 Sacramento, CA 95817, USA.
Chondroblastoma, a rare benign bone tumor, is typically found in the epiphysis of long bones, with hand involvement being particularly uncommon. We present a case of an 11-year-old female with chondroblastoma involving the fourth distal phalanx of the hand. Imaging revealed a lytic, expansile lesion with sclerotic margins and no soft tissue component.
View Article and Find Full Text PDFJ Orthop Case Rep
January 2023
Department of Orthopaedics, ACS Medical College and Hospital, Dr. MGR Educational and Research Institute, Chennai, Tamil Nadu, India.
Introduction: Chondroblastoma is a rare and benign bone neoplasm that accounts for <1% of all bone tumors. Chondroblastomas of the hand are extremely rare, while enchondromas are the most common bone tumor of the hand.
Case Report: A 14-year-old girl had complaints of pain and swelling over the base of her thumb for 1 year.
Skeletal Radiol
July 2023
Department of Orthopedic Surgery, Onze Lieve Vrouwe Gasthuis, P.O Box 95500, 1090 HM, Amsterdam, The Netherlands.
Purpose: To assess the prevalence of intraosseous cartilaginous lesions in patients with multiple osteochondromas based on total-body (TB) MRI examinations, used for screening purposes.
Subjects And Methods: Between 2013 and 2020, TB-MRI examinations were performed in 366 patients with proven multiple osteochondromas syndrome, to rule out malignant progression. For this study, presence, or absence of intraosseous central or eccentrical chondroid lesions, defined as lobulated lesions with low signal intensity on T1-weighted images, replacing bone marrow and high signal intensity equal to fluid on T2-weighted images in the bone marrow of the meta-diaphysis of (one of) the long bones, were recorded in the long bones as part of a TB-MRI protocol.
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