Fluorescent sensing system based on molecularly imprinted phase-change microcapsules and carbon quantum dots for high-efficient detection of tetracycline.

Aiming at enhancing the detection efficiency and identification accuracy of tetracycline under a high-temperature condition, this study focuses on an innovative fluorescent sensing system (MIP@CQD-PCM) based on molecularly imprinted phase-change microcapsules along with the carbon quantum dots (CQDs) embedded in their shell. This system was fabricated by microencapsulating n-eicosane as a phase change material (PCM) core within a CQDs-embedded SiO shell, followed by coating a tetracycline-templated molecularly imprinted polymer (MIP) layer onto the surface of the SiO shell. The specific recognition sites to tetracycline molecules were finally achieved by removal of tetracycline template from the MIP layer. Comprehensive characterizations and investigations on the structure and performance of the fluorescent sensing system were given to confirm its successful fabrication in accordance to our design strategy. The resultant MIP@CQD-PCM exhibits a satisfactory thermal storage capacity and phase-change cycle stability for temperature regulation and thermal management applications under a phase-change enthalpy of over 162 J/g. Most of all, a typical fluorescence-quenching effect was obtained from the combination of the CQDs embedded in the SiO shell and the tetracycline molecules adsorbed in the MIP layer. This makes the MIP@CQD-PCM achieve an enhanced capability for the fluorescence identification of tetracycline in a high-temperature environment through the in situ thermal management of its PCM core. The MIP@CQD-PCM also displays high selectivity and good reusability for tetracycline detection in industrial applications. This work provides a promising strategy for the design and development of fluorescent sensing systems with high recognition efficiency and identification accuracy in the detection of hazardous substances.