Introduction: Leishmaniasis is a vector-borne disease caused by flagellated protozoans of the genus Leishmania. This study aimed to evaluate the epidemiological status of Visceral Leishmaniasis (VL) and Cutaneous Leishmaniasis (CL) among patients admitted to a university hospital in Istanbul, located in western Turkey.
Methodology: This study included 160 and 77 patients with a pre-diagnosis of VL and CL, respectively, between January 2001 and December 2017. Detailed demographic data, including age, gender, nationality and the number and location of lesions were collected and recorded from the patient registries.
Results: Among 160 bone marrow specimens that suspected as VL, 22 (13.7%) of the specimens that were evaluated with both culture and Giemsa staining detected as positive. Furthermore, 29 (37.7%) of the 77 patients suspected for CL showed evidence of Leishmania.
Conclusions: The increase in human immigration from neighbouring countries (with a high incidence of leishmaniasis) to Turkey might increase the risk of spreading the disease. This situation could result in a higher prevalence in metropolitan cities like Istanbul, where the country's population is concentrated.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3855/jidc.12376 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Non-compaction cardiomyopathy and visceral leishmaniasis: uncommon combination with therapeutic challenges in a resource limited-setting.
Sudan J Paediatr
January 2024
Pediatric Department, Faculty of Medicine, National University, Khartoum, Sudan.
Non-compaction cardiomyopathy (NCCM) or spongy myocardium is a rare type of congenital cardiomyopathy. Visceral leishmaniasis is a protozoal disease caused by and transmitted by the bite of female sand-fly species of , which is common in tropical areas like Sudan. We report a 6-year-old female, presented with a fever of unknown origin, weight loss, anemia that necessitated multiple blood transfusions and had hepatosplenomegaly.
View Article and Find Full Text PDFElimination of visceral leishmaniasis in Ethiopia - cross-sector collaboration and costsharing to promote sustainability.
Int J Infect Dis
January 2025
The END Fund.
Background Sustainable elimination of Visceral leishmaniasis as a public health problem requires the contribution of various stakeholders led by governments efforts. An estimation of the contribution of different stakeholders was conducted focusing on the cost of diagnosis, treatment and management of visceral leishmaniasis in a hospital setting. Objectives The study aimed to estimate the cost of diagnosis, treatment and management of visceral leishmaniasis in a public hospital in Ethiopia, when including the contributions of the government and other stakeholders.
View Article and Find Full Text PDFEvaluation of SB-83, a 2-amino-thiophene derivative, against Leishmania species that cause visceral leishmaniasis.
Int Immunopharmacol
January 2025
Infectious Diseases Laboratory, Campus Ministro Reis Velloso, Federal University of Parnaíba Delta, 64202-020 Parnaíba, PI, Brazil. Electronic address:
Visceral leishmaniasis is a systemic disease that affects various internal organs and represents the most severe and fatal form of leishmaniasis. Conventional treatment presents significant challenges, such as prolonged management in hospital settings, high toxicity, and an increasing growing number of cases of resistance. In previous studies, our research group demonstrated the effective and selective activity of the 2-amino-thiophene derivative SB-83 in preclinical models of cutaneous leishmaniasis.
View Article and Find Full Text PDFGuanidines Conjugated with Cell-Penetrating Peptides: A New Approach for the Development of Antileishmanial Molecules.
Molecules
January 2025
Department of Biochemistry and Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), Araraquara 14800-060, SP, Brazil.
Leishmaniasis is a neglected tropical disease caused by a protozoan of the genus Leishmania, which has visceral and cutaneous forms. The symptoms of leishmaniasis include high fever and weakness, and the cutaneous infection also causes lesions under the skin. The drugs used to treat leishmaniasis have become less effective due to the resistance mechanisms of the protozoa.
View Article and Find Full Text PDFOccurrence of Leishmania spp. in phlebotomine sand flies and dogs in Guelma region, North-eastern Algeria.
Vet Parasitol Reg Stud Reports
January 2025
Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy; Department of Veterinary Clinical Sciences, City University of Hong Kong, Hong Kong. Electronic address:
Leishmania spp. are sand fly-borne parasitic protozoa of worldwide distribution that may severely affect the health and welfare of dogs as well as of other mammalian species, including humans. Algeria is among the most affected countries, counting several cases of Leishmania infantum infection in humans and dogs.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!