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Clinical Course of Isolated Recurrent, Persistent Complex Perianal Fistulas Without Luminal Crohn's Disease: A Multicenter Case Series of 24 Patients.
Crohns Colitis 360
October 2024
Gastroenterology Associates Inc. (Powered by GI Alliance), The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Background: Isolated complex perianal fistulas, without luminal evidence of inflammatory bowel disease in the gastrointestinal tract, pose diagnostic and treatment dilemmas for gastroenterologists and colorectal surgeons. For patients who develop recurrent complex fistulas, a presumptive diagnosis of Crohn's disease may be made. It is unclear whether these cases of isolated perianal disease in the absence of luminal inflammation truly represent isolated severe cryptoglandular fistulas or rather an early presentation of Crohn's disease.
View Article and Find Full Text PDFAnal tuberculosis presented as chronic perianal abscess in an immunocompetent adult: A rare case report.
J Family Med Prim Care
October 2024
Department of Pediatrics, AIIMS Deoghar, Devipur, Jharkhand, India.
There are reported 7.5 million cases of extra pulmonary tuberculosis (TB) (EPTB) worldwide and 19% in the South-East Asia region. Anal TB represents an exceedingly uncommon extra pulmonary manifestation of TB), occurring in fewer than 1% of individuals who acquire TB.
View Article and Find Full Text PDFMesh-related complications and recurrence after incisional hernia repair in patients with fistulizing versus non-fistulizing Crohn's disease.
Hernia
November 2024
Department of Surgery, North Denmark Regional Hospital Hjørring, Hjørring, Denmark.
Purpose: Patients with Crohn's disease (CD) frequently undergo multiple abdominal operations, which increase the risk of incisional hernia repair (IHR) and associated mesh-related complications. Patients with intra-abdominal fistulizing CD (FCD) may be more susceptible to mesh-related complications than patients with non-fistulizing CD (non-FCD). The primary objective was to evaluate the risk of reoperation due to mesh-related complications after IHR in patients with FCD and non-FCD.
View Article and Find Full Text PDFPerianal Comedones: A Variant of Hidradenitis Suppurativa or an Isolated Entity? Five-Case Report.
Actas Dermosifiliogr
November 2024
Departamento de Dermatología, Hospital Universitari Germans Trias i Pujol, Institut Investigació Germans Trias i Pujol (IGTP), Badalona, Barcelona, España.
Although comedones are a prevalent entity in multiple skin diseases, their perianal location as a cluster is a rare finding. We describe 5 patients with grouped perianal comedones who developed the lesions in adulthood and were treatment-naïve in the perianal area. Four of them had had inflammatory lesions in armpits and groins.
View Article and Find Full Text PDFFirst documentation of a clinical multidrug-resistant Enterobacter chuandaensis ST2493 isolate co-harboring bla and two bla bearing plasmids.
Sci Rep
November 2024
Department of Laboratory Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Article Synopsis
- The study highlights the rise of carbapenem-resistant Enterobacter chuandaensis, a rare member of the Enterobacter cloacae complex, complicating infection treatment.
- Researchers identified a specific strain, FAHZZU5885, from a patient in ICU, which carried multiple resistance genes and exhibited resistance to most antibiotics except a few.
- Genetic analysis revealed that the strain harbored two different plasmids containing carbapenemase genes, raising concerns about its potential to spread and contribute to further resistance issues.
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