The turbulent smoke dispersion from a pool fire around a cubical building is studied using large eddy simulation at a high Reynolds number, corresponding to existing experimental measurements both in laboratory and field test scales. Emphasis of this work is on the smoke dispersion due to two different fuel pool fire accident scenarios, initiated behind the building. For the setup of fire in the first case, crude oil was used with a heat release rate of 7.8 MW, and in the second, diesel oil with a heat release rate of 13.5 MW. It is found that in both fire scenarios, the downstream extent of the toxic zone is approximately the same. This is explained in terms of the fact that the smoke concentration and dispersion are influenced mainly by the convective buoyant forces and the strong turbulence mixing processes within the wake zone of the building. It is suggested that wind is the dominating factor in these accident scenarios, which represent the conditions resulting in the highest toxicity levels.
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http://dx.doi.org/10.1007/s11356-021-13604-3 | DOI Listing |
Nat Rev Drug Discov
January 2025
Euler Institute, Faculty of Biomedical Sciences, Università della Svizzera italiana (USI), Lugano, Switzerland.
G protein-coupled receptors (GPCRs) are the largest human membrane protein family that transduce extracellular signals into cellular responses. They are major pharmacological targets, with approximately 26% of marketed drugs targeting GPCRs, primarily at their orthosteric binding site. Despite their prominence, predicting the pharmacological effects of novel GPCR-targeting drugs remains challenging due to the complex functional dynamics of these receptors.
View Article and Find Full Text PDFSci Rep
December 2024
Climate and Global Dynamics Laboratory, NSF National Center for Atmospheric Research, 1850 Table Mesa Drive, Boulder, CO, 80305, USA.
The warm Western Boundary Currents (WBCs) and their zonal extensions are persistent, deep, strong and narrow oceanic currents. They are known to anchor and energize the Extra-Tropical storm tracks by frontal thermal air-sea interactions. However, even in the latest generation of climate models, WBCs are characterized by large biases, and both the present storm-track activity and its recent intensification are poorly estimated.
View Article and Find Full Text PDFNat Commun
December 2024
Frontiers Science Center for Deep Ocean Multispheres and Earth System, and Key Laboratory of Physical Oceanography, Ministry of Education, the College of Oceanic and Atmospheric Sciences, Ocean University of China, and Laoshan Laboratory, Qingdao, China.
A shift in depth range enables marine organisms to adapt to marine heatwaves (MHWs). Subsurface MHWs could limit this pathway, yet their response to climate warming remains unclear. Here, using an eddy-resolving Earth system model forced under a high emission scenario, we project a robust global increase in subsurface MHWs driven by rising subsurface mean temperatures and enhanced temperature variability.
View Article and Find Full Text PDFSci Total Environ
December 2024
Applied Chemistry and Environmental Science, RMIT University, GPO Box 2476, Melbourne, Victoria 3001, Australia. Electronic address:
Peatlands are important global stores of carbon. However, peatland disturbance, including climate change, can cause stored carbon to be released, shifting peatlands from net carbon sinks to net carbon sources. Yet, there is a paucity of data on the carbon cycling of Australian peatlands from which to inform effective management of the peatland carbon store.
View Article and Find Full Text PDFACS Omega
December 2024
School of Energy and Power Engineering, Dalian University of Technology, Dalian 116024, PR China.
The fly ash generated by coal combustion is one of the main sources of PM2.5, so the particulate matter removal technology of coal-fired boilers is receiving increasing attention. Turbulent agglomeration has emerged as a powerful tool for improving the efficiency of removing fine particulates from environments, sparking interest in its study.
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