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Surrogates of Muscle Mass on Cardiac MRI Correlate with Exercise Capacity in Patients with Fontan Circulation.
J Clin Med
April 2023
Department of Pediatric Cardiology, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.
Background: Sarcopenia is an increasingly recognized marker of frailty in cardiac patients. Patients with a history of congenital heart disease and Fontan procedure have a higher risk of developing progressive muscle wasting. Our objective was to determine if we could use routine cardiac MRI (CMR) for the surveillance of muscle wasting.
View Article and Find Full Text PDFExercise invasive hemodynamics in adults post-Fontan: A novel tool in understanding functional limitation and liver disease.
J Heart Lung Transplant
June 2022
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Functional impairment is essentially universal among adults post-Fontan palliation. Cardiac catheterization is frequently performed in patients post-Fontan but normal resting Fontan and ventricular filling pressures are commonly recorded even in highly symptomatic individuals. Ascertaining the etiology of exertional symptoms in these individuals is further complicated by the prevalence of co-existent sarcopenia, abnormal skeletal muscle function, impaired respiratory mechanics, and deconditioning.
View Article and Find Full Text PDFSarcopenia in Fontan patients: a sign of frailty-associated premature ageing?
Cardiol Young
May 2021
McGill Adult Unit for Congenital Heart Disease Excellence, McGill University Health Centre, Montreal, Quebec, Canada.
Secondary sarcopenia assessed by computed tomography can predict hospitalization for heart failure in adults with Fontan circulation.
J Cardiol
January 2021
Department of Pediatric Cardiology and Adult Congenital Cardiology, Tokyo Women's Medical University, Tokyo, Japan. Electronic address:
Background: Sarcopenia is one of the important predictors of heart failure (HF) in patients with cardiac problems. Skeletal muscle pump is important to maintain Fontan circulation. We aimed to quantify the volume of the psoas major muscle (PMM) and investigate whether it is relevant to HF hospitalization in adults with Fontan circulation.
View Article and Find Full Text PDFLow Muscle Mass as a Prognostic Factor for Early Postoperative Outcomes in Pediatric Patients Undergoing the Fontan Operation: A Retrospective Cohort Study.
J Clin Med
August 2019
Department of Anesthesiology and Pain Medicine, Laboratory for Cardiovascular Dynamics, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.
The impact of low muscle mass on pediatric cardiac patients remains unclear. We investigated the impact of low muscle mass on early postoperative outcomes in patients undergoing the Fontan operation. The electronic medical records of 74 patients (aged <18 years) who underwent the Fontan operation were retrospectively reviewed.
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