Background: In urban environments, environmental air pollution poses significant risks to respiratory health. Moreover, the seasonal spatial variability of the air pollutant ozone, and respiratory illness within Dallas-Fort Worth (DFW) is not well understood. We examine the relationships between spatial patterns of long-term ozone exposure and respiratory illness to better understand impacts on health outcomes. We propose that this study will establish an enhanced understanding of the spatio-temporal characteristics of ozone concentrations and respiratory emergency room visits (ERV) incidence.
Methods: Air pollution data (ozone) and ERV incidence data from DFW was used to evaluate the relationships between exposures and outcomes using three steps: (1) develop a geostatistical model to produce quarterly maps of ozone exposure for the DFW area; (2) use spatial analysis techniques to identify clusters of zip codes with high or low values of ozone exposure and respiratory ERV incidence; and (3) use concentration-response curves to evaluate the relationships between respiratory ERV incidence and ozone exposure.
Results: Respiratory ERV incidence was highest in quarters 1 and 4, while ozone exposure was highest in quarters 2 and 3. Extensive statistically significant spatial clusters of ozone regions were identified. Although the maps revealed that there was no regional association between the spatial patterns of high respiratory ERV incidence and ozone exposure, the concentration-response analysis suggests that lower levels of ozone exposure may still contribute to adverse respiratory outcomes.
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http://dx.doi.org/10.7717/peerj.11066 | DOI Listing |
Environ Sci Process Impacts
January 2025
Department of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan, 450001, PR China.
: several adverse effects of ozone (O) and nitrogen dioxide (NO) are assessed using combined oxidant capacity (O) and redox-weighted oxidant capacity (Owtx) as surrogates. However, the associations of oxidant capacity (O and Owtx) with platelet-based inflammatory indicators and the potential modifying role of physical activity (PA) remain unclear. : 31 318 participants were selected from the baseline survey of the Henan Rural Cohort Study.
View Article and Find Full Text PDFEnviron Health (Wash)
January 2025
Institute of Environmental Science, Shanxi University, Taiyuan 030006, China.
Abundant epidemiological studies have conclusively demonstrated the effects of short-term ozone (O) exposure on the incidence and mortality of cardiovascular diseases. However, the mechanism of its influence remains unverified. This study aimed to assess the impact of O on metabolomic-based biomarkers in acute myocardial infarction (AMI) patients.
View Article and Find Full Text PDFFront Physiol
January 2025
Department of Sport Medicine and Traumatology, Poznan Univeristy of Physical Education, Poznań, Poland.
Swimming produces many psychophysiological effects, including blood, hormonal, enzymatic, pulmonary, cardiovascular and energetic adaptations. However, asthma and allergies are becoming increasingly prevalent medical issues among elite endurance-trained swimmers, where exercise-induced asthma or bronchospasm is frequently reported. Heavy endurance swimming training, especially under adverse conditions, stresses the airway mucosa, leading to inflammatory changes, as observed in induced sputum in competitive swimmers.
View Article and Find Full Text PDFChem Res Toxicol
January 2025
Department of Environmental Sciences, University of California, Riverside, California 92521, United States.
E-cigarette emissions, which contain a variety of hazardous compounds, contribute significantly to indoor air pollution and raise concerns about secondhand exposure to vaping byproducts. Compared to fresh vape emissions, our understanding of chemically aged products in indoor environments remains incomplete. Terpenes are commonly used as flavoring agents in e-liquids, which have the ability to react with the dominant indoor oxidant ozone (O) to produce reactive oxygenated byproducts and result in new particle formation.
View Article and Find Full Text PDFAm J Physiol Lung Cell Mol Physiol
January 2025
Department of Pharmacology and Toxicology, University of Utah College of Pharmacy, Salt Lake City, UT, USA.
Ozone (O) is a ubiquitous pollutant known to produce acute, transient inflammation through oxidative injury and inflammation. These effects are exacerbated in susceptible populations, such as the elderly and those exhibiting genetic mutations in central nodes of pulmonary function. To comprehend the impact of these predisposing factors, the present study examines structural, mechanical, and immunological responses to single acute O exposure (0.
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