Periodic occurrences of oligonucleotide sequences can impact the physical properties of DNA. For example, DNA bendability is modulated by 10-bp periodic occurrences of WW (W = A/T) dinucleotides. We present periodicDNA, an R package to identify k-mer periodicity and generate continuous tracks of k-mer periodicity over genomic loci of interest, such as regulatory elements. periodicDNA will facilitate investigation and improve understanding of how periodic DNA sequence features impact function.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063535 | PMC |
| http://dx.doi.org/10.12688/f1000research.51143.1 | DOI Listing |
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