The reverse projection protocol results in fast phase-contrast imaging thanks to its compatibility with conventional computed-tomography scanning. Many researchers have proposed variants. However, all these reverse projection methods in grating-based phase-contrast imaging are built on the hypothesis of the synchronous phase of reference shifting curves in the whole field of view. The hypothesis imposes uniformity and alignment requirements on the gratings, thus the field of view is generally limited. In this paper, a generalized reverse projection method is presented analytically for the case of non-uniform reference in grating-based phase tomography. The method is demonstrated by theoretical derivation, numerical simulations and synchrotron radiation experiments. The influence of imaging position to sensitivity, and the phase-wrapping phenomenon are also discussed. The proposed method combines the advantages of the high efficiency of the reverse projection method and the universal applicability of the phase-stepping method. The authors believe that the method would be used widely in fast and dose-constrained imaging.
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http://dx.doi.org/10.1107/S1600577521001806 | DOI Listing |
Front Cell Infect Microbiol
January 2025
State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Introduction: Respiratory syncytial virus (RSV) remains a major international public health concern. However, disease treatment is limited to preventive care with monoclonal antibodies and supportive care. In this study, natural products were screened to identify novel anti-RSV inhibitors.
View Article and Find Full Text PDFUlus Travma Acil Cerrahi Derg
January 2025
Department of Neurosurgery, Gulhane School of Medicine, University of Health Sciences, Ankara-Türkiye.
Background: Acute subdural hematoma (ASDH) is a critical and often fatal condition, particularly in elderly patients receiving anticoagulant therapy. With a growing global aging population, the incidence of traumatic brain injuries, including ASDH, is projected to rise, presenting significant challenges in clinical management. This study evaluates the outcomes of surgically treated ASDH in patients aged 65 years and older, comparing those who received anticoagulant therapy with those who did not.
View Article and Find Full Text PDFAntibiotics (Basel)
November 2024
Pharmacy Department, Asl Napoli 3 Sud, Dell'amicizia Street 22, 80035 Nola, Italy.
Antimicrobial resistance (AMR) has emerged as a significant challenge to public health, posing a considerable threat to effective disease management on a global scale. The increasing incidence of infections caused by resistant bacteria has led to heightened morbidity and mortality rates, particularly among vulnerable populations. This review analyzes current strategies and health policies adopted in the European Union (EU) and Italy to manage AMR, presenting an in-depth examination of approaches for containment and mitigation.
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December 2024
Department of Pathophysiology, School of Basic Medicine, Qingdao University, Qingdao, Shandong, China.
Objective: The ventral tegmental area (VTA), a pivotal hub in the brain's reward circuitry, receives inputs from the lateral hypothalamic area (LHA). However, it remains unclear whether melanin-concentrating hormone (MCH) and orexin-A (OX-A) neurons in the LHA exert individual or cooperative influence on palatable food consumption in the VTA. This study aims to investigate the modulatory role of MCH and OX-A in hedonic feeding within the VTA of high-fat diet (HFD) mice.
View Article and Find Full Text PDFPhotochem Photobiol Sci
January 2025
Institute of Meteorology and Climate Research Atmospheric Trace Gases and Remote Sensing, Karlsruhe Institute of Technology, Karlsruhe, Germany.
For a given solar elevation, the levels of solar ultraviolet radiation at the Earth's surface are determined by the amounts of ozone, aerosols, and clouds, as well as by the reflectivity of the surface. Here, we study the evolution of these factors for three selected decades in the period 1950-2100 using results from simulations with Earth-System models (ESMs) participating in the 6 phase of the Coupled Model Intercomparison Project (CMIP6). The simulations for the future are based on three Shared Socioeconomic Pathways: SSP1-2.
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