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Endocrine alterations in patients with pachydermoperiostosis.
J Clin Endocrinol Metab
January 2025
Centre for Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Context: Pachydermoperiostosis (primary hypertrophic osteoarthropathy, PHO) usually due to biallelic loss-of-function variants in HPGD and SLCO2A1, has some features overlapping with acromegaly and often referred to endocrinologists. A detailed endocrine assessment is not available for these patients.
Objective: To assess the genetic and endocrine characteristics of PHO patients referred to endocrine centres with a possible diagnosis of acromegaly.
A Deep Learning Framework for Automated Classification and Archiving of Orthodontic Diagnostic Documents.
Cureus
December 2024
Department of Orthodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, IRN.
Background Orthodontic diagnostic workflows often rely on manual classification and archiving of large volumes of patient images, a process that is both time-consuming and prone to errors such as mislabeling and incomplete documentation. These challenges can compromise treatment accuracy and overall patient care. To address these issues, we propose an artificial intelligence (AI)-driven deep learning framework based on convolutional neural networks (CNNs) to automate the classification and archiving of orthodontic diagnostic images.
View Article and Find Full Text PDFEffect of a chemically-modified-curcumin on dental resin biodegradation.
Front Oral Health
January 2025
Department of General Dentistry, School of Dental Medicine, Stony Brook University, Stony Brook, NY, United States.
Introduction: Previous studies have shown () esterase is a key mediator of dental composite biodegradation, which can contribute to recurrent caries. This study is to investigate the inhibitory effects of a novel Chemically-Modified-Curcumin (CMC 2.24) on esterase activities and related dental material biodegradation.
View Article and Find Full Text PDFInterdisciplinary Approach to Retreatment of a Full-Mouth Rehabilitation: Horizontal Preparations, Vertical Dimension of Occlusion Increase, and Mucogingival Surgery in a Tetracycline-Stained Dentition.
J Esthet Restor Dent
January 2025
Analysis of Techniques, Material and Instruments Applied to Digital Dentistry and CAD/CAM Procedures Research Group, Complutense University of Madrid, Madrid, Spain.
Objective: This case report presents the interdisciplinary retreatment of a patient with a worn full-mouth rehabilitation using defect-oriented restorations, horizontal preparations, and vertical dimension of occlusion (VDO) increase.
Clinical Considerations: A 58-year-old woman with a previous full-mouth rehabilitation presented with worn dentition, loss of VDO, and reduced posterior support. Examination revealed signs of parafunctional habits, tetracycline-stained teeth, and compromised aesthetics with exposed discolored teeth and open embrasure spaces.
Development of Electronic Objective Structured Clinical Examinations (e-OSCEs) for Prosthodontic Clinical Assessment.
Eur J Dent Educ
January 2025
Department of Prosthodontics, New York University College of Dentistry, New York, New York, USA.
Introduction: Objective Structured Clinical Examinations (OSCEs) serve as a reliable assessment tool for clinical and competency evaluation. Traditional OSCEs, involving live patients, present logistical challenges and evoke student anxiety. In an effort to create a comprehensive clinical series of examinations, electronic OSCEs (e-OSCEs) were developed for assessing clinical competencies in prosthodontics at a large dental school.
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