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Prevalence of COVID-19 in children, adolescents and adults in remote education situations in the city of Fortaleza, Brazil. | LitMetric

AI Article Synopsis

  • A retrospective study analyzed the prevalence of COVID-19 in children, adolescents, and adults using serology and RT-PCR data from a COVID-19 Tracking Program in schools.
  • The study found that 25.3% of children, 29.2% of adolescents, and 20.9% of adults had positive serological test results, with lower incidence of symptoms noted in children compared to the other age groups.
  • Overall, the prevalence rates were 26.7% for serology and 4.04% for RT-PCR across all groups, indicating a potential for COVID-19 transmissibility in all ages.

Article Abstract

Objectives: A retrospective study was conducted to identify the prevalence of COVID-19 through serology and RT-PCR in children, adolescents and adults. A database of the COVID-19 Tracking Program in school children was used.

Methods: The data comprised sociodemographic and clinical variables, results of serological tests (IgM and IgG), and real-time-polymerase chain reaction (RT-PCR) results of IgM-positive individuals. The statistical analysis was performed with a 5% significance level.

Results: Among 423 children, 107 (25.3%) exhibited seroprevalence with IgG, IgM or IgG/IgM; among 854 adolescents, 250 (29.2%) had positive serology; and among 282 adults, 59 (20.9%) were positive. The frequency of positivity on RT-PCR for SARS-CoV-2 was 3.5%, 3.6% and 6.0% in children, adolescents and adults, respectively. Children had a lower incidence of symptoms than adolescents (p = 0.001) and adults (p = 0.003); the most frequent were fever, ageusia, anosmia, headache, dry cough, sore throat, muscle pain, runny nose, dyspnoea, and diarrhoea.

Conclusions: The prevalence rate for all groups was 26.7% in serology and 4.04% in RT-PCR. Children had lower rates of IgM and fewer symptoms compared with adolescents and adults. The data suggest the potential for transmissibility in all age groups.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088039PMC
http://dx.doi.org/10.1016/j.ijid.2021.04.086DOI Listing

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