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http://dx.doi.org/10.1164/rccm.202103-0809ED | DOI Listing |
J Cardiol
January 2025
Department of Cardiology, St. Luke's University Health Network, Bethlehem, PA, USA. Electronic address:
Background: Hypertrophic cardiomyopathy (HCM) is a common genetic disease with estimated prevalence of 0.2-0.5 %.
View Article and Find Full Text PDFBiochem Biophys Res Commun
January 2025
Department of Neurosurgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200433, China. Electronic address:
Objective: Gliomas pose a significant global health challenge due to high rates of morbidity and mortality. Recent research has indicated that circular RNAs (circRNAs) may play a crucial role in gliomas. However, the specific impacts of circRNAs on gliomas development is poorly understood.
View Article and Find Full Text PDFAm J Emerg Med
January 2025
Samaritan Health Services, 2300 NW Walnut Blvd. Corvallis, OR 97330, United States of America. Electronic address:
Introduction: We investigated the extent to which demographic characteristics, clinical care aspects, and relevant biomarkers predicted sepsis-related mortality among patients transferred from a rural, low-volume emergency department (ED) to an urban, high-volume, level-2 trauma center.
Methods: We conducted an observational study among adult severe sepsis patients (N = 242) who, within a community-based regional healthcare system, presented to one of the four rural, low-volume EDs and were subsequently transferred to the urban, high-volume, level-2 trauma center, and were identified as septic at either location. We evaluated in-hospital and 30 days after discharge mortality.
Int J Surg Case Rep
January 2025
Al-Neelain University, Faculty of Medicine, Khartoum, Sudan.
Introduction And Importance: Severe aortic stenosis (AS) and chronic obstructive pulmonary disease (COPD) significantly increase perioperative morbidity and mortality. This case report discusses the challenges of managing a 75-year-old male patient with severe AS and advanced COPD undergoing elective abdominal aortic aneurysm (AAA) repair.
Case Presentation: The patient presented with a 6.
Biomarkers
January 2025
Pediatric Intensive Care Unit, Hospital Sant Joan de Déu-University of Barcelona, Barcelona, Spain.
PurposeChimeric antigen receptor (CAR) T-cell CD19 therapy has changed the treatment paradigm for patients with relapsed/refractory B-cell acute lymphoblastic leukemia. It is frequently associated with potentially severe toxicities: cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS), and admission to PICU is often required. Some biomarkers seem to correlate with CRS severity.
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