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Background: Several cases of glomerular diseases following Covid-19 vaccination, especially mRNA vaccines, have been reported. However, there is little data on glomerular diseases associated with the two vaccines widely available in India (Covaxin and Covishield) and their long-term outcomes.

Materials And Methods: This was a prospective observational study conducted between May 2021 and May 2023.

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Article Synopsis
  • Vasculitis is a potential complication of COVID-19, where the virus can trigger or worsen autoimmune diseases like systemic vasculitis.
  • The case of an elderly patient with multiple health issues highlighted the connection, as doctors diagnosed vasculitis due to renal function decline and positive antinuclear antibodies.
  • A kidney biopsy confirmed focal necrotizing and crescentic glomerulonephritis, emphasizing the need for awareness of COVID-19 related complications and a broad differential diagnosis in recovering patients.
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[ANCA-Associated Glomerulonephritis Following SARS-CoV2 Infection: A Case Report].

G Ital Nefrol

October 2024

UOC Pronto Soccorso e Medicina d'Urgenza, P.O. San Filippo Neri, ASL Roma 1, Roma.

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  • Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) primarily targets small- and medium-sized arteries, leading to conditions like rapidly progressive glomerulonephritis, particularly affecting the kidneys.
  • Infections are known triggers for this autoimmune disorder, and recent studies suggest a link between SARS-CoV-2 infection and acute kidney injury (AKI).
  • The text presents a specific case of a 61-year-old man who developed new-onset diffuse proliferative ANCA-associated glomerulonephritis following COVID-19.
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A case of de novo glomerulonephritis following COVID-19 in a patient with preexistent IgA vasculitis.

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October 2024

Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Shimane University, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan.

Article Synopsis
  • * A case study discusses a young Japanese woman with preexisting IgAV who developed glomerulonephritis after contracting COVID-19, experiencing symptoms like hematuria and proteinuria following her illness.
  • * After a renal biopsy confirmed her condition, she was treated with corticosteroids and showed significant improvement, indicating that COVID-19 may provoke kidney issues in IgAV patients without prior renal symptoms.
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Article Synopsis
  • A study assessed the trends in various vasculitis conditions in Israel from 2007 to 2021, particularly during the COVID-19 pandemic.
  • The incidence rates of giant cell arteritis, IgA vasculitis, and Behcet's disease significantly decreased over the years, while Takayasu, ANCA-associated vasculitis, and cryoglobulinemia showed no changes.
  • The COVID-19 pandemic had no impact on the incidence rates of any of the examined vasculitides, suggesting that future research should explore environmental factors influencing these trends.
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