Diclofenac and dexamethasone injection mixture could be associated with fatal cardiovascular events, further studies are warrantied to explore the safety of this injection mixture and explore the genetic role of it.
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http://dx.doi.org/10.1002/ccr3.3988 | DOI Listing |
J Biomed Mater Res A
January 2025
Department of Bioengineering, Lehigh University, Bethlehem, Pennsylvania, USA.
Peptides are widely used in biomaterials due to their ease of synthesis, ability to signal cells, and modify the properties of biomaterials. A key benefit of using peptides is that they are natural substrates for cell-secreted enzymes, which creates the possibility of utilizing cell-secreted enzymes for tuning cell-material interactions. However, these enzymes can also induce unwanted degradation of bioactive peptides in biomaterials, or in peptide therapies.
View Article and Find Full Text PDFInflammopharmacology
January 2025
Department of Critical Care Medicine, Xi'an No. 9 Hospital, Xi'an, 710000, Shaanxi Province, China.
Objective: The aim of this study was to comprehensively investigate the clinical efficacy of intraoperative local joint injection and intramuscular injection of betamethasone in patients with severe traumatic knee osteoarthritis (KOA).
Methods: 80 patients with severe traumatic KOA undergoing total knee arthroplasty were retrospectively recruited and rolled into S1 group (intra-articular injection of ropivacaine + betamethasone and isotonic saline mixture at joint incision), S2 group (muscle local injection of betamethasone before incision closure, simultaneously intra-articular injection of ropivacaine + isotonic saline mixture at joint incision), and D group (intra-articular injection of ropivacaine + isotonic saline mixture at the joint incision). Visual analog scale (VAS) score, serum inflammatory factors (IFs), hospital for special surgery (HSS)score, Pittsburgh sleep quality index (PSQI), and adverse reaction events (AREs) were analyzed.
Heliyon
January 2025
Gas Company of Hormozgan Province, National Iranian Gas Company, Hormozgan, Iran.
The absence of a mercaptan compounds analyzer in natural gas pressure reduction stations (PRS) odorizer leads to inaccuracies in the injection dosage, often resulting in quantities beyond standard limits and consequently increasing odorant consumption. Insufficient odorant levels in natural gas can pose safety risks to consumers, as the gas may become odorless at the end of the pipeline. Therefore, accurate determination of the concentration of key odorant compounds in natural gas can reduce both costs and environmental risks.
View Article and Find Full Text PDFJ Small Anim Pract
January 2025
Department of Veterinary Science, University of Turin, Grugliasco, Italy.
Objectives: To evaluate the perioperative efficacy of a modified supratemporal retrobulbar block in dogs undergoing ocular surgery.
Materials And Methods: In this prospective randomized clinical trial, dogs were premedicated with dexmedetomidine (1 mcg/kg im) and methadone (0.1 mg/kg im), induced with propofol to effect and maintained with isoflurane (FE'Iso 1.
Chemosphere
January 2025
Ramboll, 3401 Enterprise Place, Suite 340, Beachwood, Ohio 44122, USA. Electronic address:
Egg injection has been used for decades to determine embryonic mortality and developmental effects of chemical exposures in birds. Specific egg injection methods affect how well these studies replicate the process of chemical delivery to the embryo via maternal deposition, yet few data are available to compare exposure-response relationships between egg injection and maternal transfer studies. This information gap creates uncertainty when considering egg injection studies for assessment of potential adverse effects in wild birds.
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