Bevacizumab is a monoclonal antibody against vascular endothelial growth factor that exerts antitumor effect by preventing tumor angiogenesis. Gastrointestinal fistula is a common side effect of bevacizumab in combination with radiotherapy. This case of rectovaginal fistula indicates that the side effect may be unpredictable by the conventional dose-volume parameters for the rectum.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077241PMC
http://dx.doi.org/10.1002/ccr3.3955DOI Listing

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